SNP Detail Info-rs7644500

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0175 (5259/29894,GnomAD)
A=0209 (6099/29118,TOPMED)
A=0221 (1108/5008,1000G)
A=0109 (420/3854,ALSPAC)
A=0105 (390/3708,TWINSUK)

Position: chr3:161506750 (GRCh38.p7) (3q26.1)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 5 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 3	NC_000003.12:g.161506750G>A
GRCh37.p13 chr 3	NC_000003.11:g.161224538G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.623	A=0.377
1000Genomes	American	Sub	694	G=0.880	A=0.120
1000Genomes	East Asian	Sub	1008	G=0.885	A=0.115
1000Genomes	Europe	Sub	1006	G=0.902	A=0.098
1000Genomes	Global	Study-wide	5008	G=0.779	A=0.221
1000Genomes	South Asian	Sub	978	G=0.680	A=0.320
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.891	A=0.109
The Genome Aggregation Database	African	Sub	8680	G=0.667	A=0.333
The Genome Aggregation Database	American	Sub	838	G=0.890	A=0.110
The Genome Aggregation Database	East Asian	Sub	1606	G=0.853	A=0.147
The Genome Aggregation Database	Europe	Sub	18468	G=0.892	A=0.107
The Genome Aggregation Database	Global	Study-wide	29894	G=0.824	A=0.175
The Genome Aggregation Database	Other	Sub	302	G=0.860	A=0.140
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.790	A=0.209
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.895	A=0.105

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs7644500	9.51E-06	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr3	161270739	161271083	E070	46201
chr3	161193863	161193967	E072	-30571
chr3	161194359	161194474	E072	-30064
chr3	161193863	161193967	E074	-30571
chr3	161194359	161194474	E074	-30064

rs7644500