rs7650925

Homo sapiens
G>T
SRPRB : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0475 (13772/28950,GnomAD)
G==0346 (1731/5008,1000G)
chr3:133808325 (GRCh38.p7) (3q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
108 Enhancers around
19 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.133808325G>T
GRCh37.p13 chr 3NC_000003.11:g.133527169G>T

Gene: SRPRB, SRP receptor beta subunit(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SRPRB transcriptNM_021203.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.219T=0.781
1000GenomesAmericanSub694G=0.460T=0.540
1000GenomesEast AsianSub1008G=0.281T=0.719
1000GenomesEuropeSub1006G=0.477T=0.523
1000GenomesGlobalStudy-wide5008G=0.346T=0.654
1000GenomesSouth AsianSub978G=0.370T=0.630
The Genome Aggregation DatabaseAfricanSub8542G=0.266T=0.734
The Genome Aggregation DatabaseAmericanSub796G=0.700T=0.300
The Genome Aggregation DatabaseEast AsianSub1604G=0.720T=0.280
The Genome Aggregation DatabaseEuropeSub17716G=0.623T=0.376
The Genome Aggregation DatabaseGlobalStudy-wide28950G=0.524T=0.475
The Genome Aggregation DatabaseOtherSub292G=0.540T=0.460
PMID Title Author Journal
21665994Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.Kutalik ZHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs76509252.74E-11alcohol consumption21665994

eQTL of rs7650925 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7650925 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3133482923133483028E067-44141
chr3133483054133483594E067-43575
chr3133483998133484070E067-43099
chr3133562885133562960E06735716
chr3133573215133573347E06746046
chr3133573885133574171E06746716
chr3133574725133574824E06747556
chr3133575303133575377E06748134
chr3133482562133482616E068-44553
chr3133482923133483028E068-44141
chr3133483054133483594E068-43575
chr3133572273133572376E06845104
chr3133572430133572579E06845261
chr3133572588133572638E06845419
chr3133573215133573347E06846046
chr3133573885133574171E06846716
chr3133574725133574824E06847556
chr3133575303133575377E06848134
chr3133482562133482616E069-44553
chr3133482923133483028E069-44141
chr3133483054133483594E069-43575
chr3133483998133484070E069-43099
chr3133484337133484387E069-42782
chr3133540603133541021E06913434
chr3133541191133541245E06914022
chr3133572273133572376E06945104
chr3133572430133572579E06945261
chr3133572588133572638E06945419
chr3133573215133573347E06946046
chr3133573885133574171E06946716
chr3133574725133574824E06947556
chr3133575303133575377E06948134
chr3133482923133483028E070-44141
chr3133483054133483594E070-43575
chr3133547093133547193E07019924
chr3133547516133547745E07020347
chr3133547924133548172E07020755
chr3133572273133572376E07045104
chr3133572430133572579E07045261
chr3133572588133572638E07045419
chr3133573215133573347E07046046
chr3133573885133574171E07046716
chr3133574725133574824E07047556
chr3133575303133575377E07048134
chr3133482562133482616E071-44553
chr3133482923133483028E071-44141
chr3133483054133483594E071-43575
chr3133483998133484070E071-43099
chr3133484337133484387E071-42782
chr3133540337133540417E07113168
chr3133572273133572376E07145104
chr3133572430133572579E07145261
chr3133572588133572638E07145419
chr3133573215133573347E07146046
chr3133573885133574171E07146716
chr3133574725133574824E07147556
chr3133482923133483028E072-44141
chr3133483054133483594E072-43575
chr3133483998133484070E072-43099
chr3133484337133484387E072-42782
chr3133573215133573347E07246046
chr3133573885133574171E07246716
chr3133574725133574824E07247556
chr3133482923133483028E073-44141
chr3133483054133483594E073-43575
chr3133540006133540074E07312837
chr3133540337133540417E07313168
chr3133540603133541021E07313434
chr3133541035133541081E07313866
chr3133541191133541245E07314022
chr3133572273133572376E07345104
chr3133573215133573347E07346046
chr3133573885133574171E07346716
chr3133574725133574824E07347556
chr3133575303133575377E07348134
chr3133482562133482616E074-44553
chr3133482923133483028E074-44141
chr3133483054133483594E074-43575
chr3133483998133484070E074-43099
chr3133484337133484387E074-42782
chr3133540006133540074E07412837
chr3133540337133540417E07413168
chr3133540603133541021E07413434
chr3133541035133541081E07413866
chr3133541191133541245E07414022
chr3133541431133541497E07414262
chr3133541623133541762E07414454
chr3133541910133541964E07414741
chr3133572430133572579E07445261
chr3133572588133572638E07445419
chr3133573215133573347E07446046
chr3133573885133574171E07446716
chr3133574725133574824E07447556
chr3133526132133526214E081-955
chr3133572273133572376E08145104
chr3133573215133573347E08146046
chr3133573885133574171E08146716
chr3133574725133574824E08147556
chr3133547516133547745E08220347
chr3133547924133548172E08220755
chr3133548284133548391E08221115
chr3133572273133572376E08245104
chr3133572430133572579E08245261
chr3133572588133572638E08245419
chr3133573215133573347E08246046
chr3133573885133574171E08246716
chr3133574725133574824E08247556
chr3133575303133575377E08248134










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3133524082133525550E067-1619
chr3133525588133525634E067-1535
chr3133524082133525550E068-1619
chr3133525588133525634E068-1535
chr3133524082133525550E069-1619
chr3133524082133525550E070-1619
chr3133525588133525634E070-1535
chr3133524082133525550E071-1619
chr3133525588133525634E071-1535
chr3133524082133525550E072-1619
chr3133525588133525634E072-1535
chr3133524082133525550E073-1619
chr3133525588133525634E073-1535
chr3133524082133525550E074-1619
chr3133525588133525634E074-1535
chr3133524082133525550E081-1619
chr3133525588133525634E081-1535
chr3133524082133525550E082-1619
chr3133525588133525634E082-1535