rs7653239

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0138 (4135/29948,GnomAD)
A=0153 (4479/29118,TOPMED)
A=0160 (799/5008,1000G)
A=0099 (382/3854,ALSPAC)
A=0082 (304/3708,TWINSUK)
chr3:33248104 (GRCh38.p7) (3p22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
45 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.33248104G>A
GRCh37.p13 chr 3NC_000003.11:g.33289596G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.752A=0.248
1000GenomesAmericanSub694G=0.900A=0.100
1000GenomesEast AsianSub1008G=0.745A=0.255
1000GenomesEuropeSub1006G=0.911A=0.089
1000GenomesGlobalStudy-wide5008G=0.840A=0.160
1000GenomesSouth AsianSub978G=0.950A=0.050
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.901A=0.099
The Genome Aggregation DatabaseAfricanSub8710G=0.763A=0.237
The Genome Aggregation DatabaseAmericanSub838G=0.940A=0.060
The Genome Aggregation DatabaseEast AsianSub1608G=0.682A=0.318
The Genome Aggregation DatabaseEuropeSub18492G=0.920A=0.079
The Genome Aggregation DatabaseGlobalStudy-wide29948G=0.861A=0.138
The Genome Aggregation DatabaseOtherSub300G=0.890A=0.110
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.846A=0.153
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.918A=0.082
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs76532390.000204alcohol dependence21314694

eQTL of rs7653239 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7653239 in Fetal Brain

Probe ID Position Gene beta p-value
cg20854551chr18:616037890.01265092541826848.4993e-10

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr33324512933245192E067-44404
chr33324457133244721E072-44875
chr33324512933245192E072-44404
chr33332170633321808E08132110
chr33332208633322146E08132490



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr33325920833259505E067-30091
chr33325950633260797E067-28799
chr33326080433260962E067-28634
chr33331860633319450E06729010
chr33331956433320166E06729968
chr33325908933259167E068-30429
chr33325920833259505E068-30091
chr33325950633260797E068-28799
chr33326080433260962E068-28634
chr33331860633319450E06829010
chr33331956433320166E06829968
chr33325920833259505E069-30091
chr33325950633260797E069-28799
chr33331860633319450E06929010
chr33331956433320166E06929968
chr33331860633319450E07029010
chr33331956433320166E07029968
chr33325908933259167E071-30429
chr33325920833259505E071-30091
chr33325950633260797E071-28799
chr33326080433260962E071-28634
chr33331860633319450E07129010
chr33331956433320166E07129968
chr33325908933259167E072-30429
chr33325920833259505E072-30091
chr33325950633260797E072-28799
chr33326080433260962E072-28634
chr33331860633319450E07229010
chr33331956433320166E07229968
chr33325908933259167E073-30429
chr33325920833259505E073-30091
chr33325950633260797E073-28799
chr33326080433260962E073-28634
chr33331860633319450E07329010
chr33331956433320166E07329968
chr33325920833259505E074-30091
chr33325950633260797E074-28799
chr33331860633319450E07429010
chr33331956433320166E07429968
chr33331956433320166E08129968
chr33325920833259505E082-30091
chr33325950633260797E082-28799
chr33326080433260962E082-28634
chr33331860633319450E08229010
chr33331956433320166E08229968