rs7655182

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0422 (12604/29868,GnomAD)
A=0442 (12873/29118,TOPMED)
A=0462 (2314/5008,1000G)
A=0352 (1358/3854,ALSPAC)
A=0342 (1269/3708,TWINSUK)
chr4:87984751 (GRCh38.p7) (4q22.1)
AD
GWASdb2
3   publication(s)
See rs on genome
96 Enhancers around
30 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.87984751G>A
GRCh37.p13 chr 4NC_000004.11:g.88905903G>A
SPP1 RefSeqGeneNG_030362.1:g.14102G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.452A=0.548
1000GenomesAmericanSub694G=0.680A=0.320
1000GenomesEast AsianSub1008G=0.549A=0.451
1000GenomesEuropeSub1006G=0.651A=0.349
1000GenomesGlobalStudy-wide5008G=0.538A=0.462
1000GenomesSouth AsianSub978G=0.420A=0.580
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.648A=0.352
The Genome Aggregation DatabaseAfricanSub8696G=0.476A=0.524
The Genome Aggregation DatabaseAmericanSub832G=0.610A=0.390
The Genome Aggregation DatabaseEast AsianSub1608G=0.513A=0.487
The Genome Aggregation DatabaseEuropeSub18430G=0.629A=0.370
The Genome Aggregation DatabaseGlobalStudy-wide29868G=0.578A=0.422
The Genome Aggregation DatabaseOtherSub302G=0.630A=0.370
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.557A=0.442
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.658A=0.342
PMID Title Author Journal
19339987Age- and gender-specific modulation of serum osteopontin and interferon-alpha by osteopontin genotype in systemic lupus erythematosus.Kariuki SNGenes Immun
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res
24917428Role of osteopontin in systemic lupus erythematosus.Kaleta BArch Immunol Ther Exp (Warsz)

P-Value

SNP ID p-value Traits Study
rs76551820.000223alcohol dependence21314694

eQTL of rs7655182 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr4:88905903PKD2ENSG00000118762.3G>A4.3214e-3-22917Frontal_Cortex_BA9
Chr4:88905903PKD2ENSG00000118762.3G>A4.5000e-3-22917Cortex

meQTL of rs7655182 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr48890628988906385E067386
chr48890643388906513E067530
chr48890671788907066E067814
chr48893221788932267E06726314
chr48893233388932523E06726430
chr48893307688933198E06727173
chr48893321488933301E06727311
chr48893547888936167E06729575
chr48889608588896253E068-9650
chr48890643388906513E068530
chr48890671788907066E068814
chr48892776788927911E06821864
chr48893162088932174E06825717
chr48893221788932267E06826314
chr48893233388932523E06826430
chr48893307688933198E06827173
chr48893321488933301E06827311
chr48893547888936167E06829575
chr48893722988937345E06831326
chr48893878988940104E06832886
chr48888843188888529E069-17374
chr48890671788907066E069814
chr48893221788932267E06926314
chr48893233388932523E06926430
chr48893307688933198E06927173
chr48893321488933301E06927311
chr48893384688934086E06927943
chr48893547888936167E06929575
chr48893878988940104E06932886
chr48894886788949855E06942964
chr48889608588896253E070-9650
chr48889632688896405E070-9498
chr48889649488896574E070-9329
chr48889659388896990E070-8913
chr48892776788927911E07021864
chr48893162088932174E07025717
chr48893221788932267E07026314
chr48893233388932523E07026430
chr48890671788907066E071814
chr48892776788927911E07121864
chr48893162088932174E07125717
chr48893221788932267E07126314
chr48893233388932523E07126430
chr48893307688933198E07127173
chr48893321488933301E07127311
chr48893384688934086E07127943
chr48893547888936167E07129575
chr48893722988937345E07131326
chr48893761388937672E07131710
chr48893878988940104E07132886
chr48888820288888290E072-17613
chr48888843188888529E072-17374
chr48890373488903889E072-2014
chr48890628988906385E072386
chr48890643388906513E072530
chr48890671788907066E072814
chr48892776788927911E07221864
chr48893162088932174E07225717
chr48893221788932267E07226314
chr48893233388932523E07226430
chr48893307688933198E07227173
chr48893321488933301E07227311
chr48893384688934086E07227943
chr48893547888936167E07229575
chr48893722988937345E07231326
chr48893878988940104E07232886
chr48894886788949855E07242964
chr48888843188888529E073-17374
chr48890671788907066E073814
chr48893221788932267E07326314
chr48893233388932523E07326430
chr48893307688933198E07327173
chr48893321488933301E07327311
chr48893547888936167E07329575
chr48888843188888529E074-17374
chr48890373488903889E074-2014
chr48890643388906513E074530
chr48890671788907066E074814
chr48893162088932174E07425717
chr48893221788932267E07426314
chr48893233388932523E07426430
chr48893307688933198E07427173
chr48893321488933301E07427311
chr48893384688934086E07427943
chr48893547888936167E07429575
chr48893722988937345E07431326
chr48893878988940104E07432886
chr48889659388896990E081-8913
chr48893162088932174E08125717
chr48893221788932267E08126314
chr48893233388932523E08126430
chr48893307688933198E08127173
chr48893878988940104E08132886
chr48893321488933301E08227311
chr48893384688934086E08227943
chr48893878988940104E08232886










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr48889813488899225E067-6678
chr48892810788930183E06722204
chr48893021388930298E06724310
chr48889813488899225E068-6678
chr48889992888900120E068-5783
chr48892810788930183E06822204
chr48893021388930298E06824310
chr48889813488899225E069-6678
chr48889992888900120E069-5783
chr48892810788930183E06922204
chr48893021388930298E06924310
chr48892810788930183E07022204
chr48893021388930298E07024310
chr48889813488899225E071-6678
chr48889992888900120E071-5783
chr48892810788930183E07122204
chr48893021388930298E07124310
chr48889813488899225E072-6678
chr48889992888900120E072-5783
chr48892810788930183E07222204
chr48893021388930298E07224310
chr48889813488899225E073-6678
chr48892810788930183E07322204
chr48893021388930298E07324310
chr48889813488899225E074-6678
chr48889992888900120E074-5783
chr48892810788930183E07422204
chr48892810788930183E08122204
chr48892810788930183E08222204
chr48893021388930298E08224310