rs7683244

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0381 (11391/29878,GnomAD)
T=0412 (12016/29118,TOPMED)
T=0356 (1781/5008,1000G)
T=0366 (1412/3854,ALSPAC)
T=0367 (1359/3708,TWINSUK)
chr4:31965136 (GRCh38.p7) (4p15.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.31965136G>T
GRCh37.p13 chr 4NC_000004.11:g.31966758G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.568T=0.432
1000GenomesAmericanSub694G=0.670T=0.330
1000GenomesEast AsianSub1008G=0.636T=0.364
1000GenomesEuropeSub1006G=0.669T=0.331
1000GenomesGlobalStudy-wide5008G=0.644T=0.356
1000GenomesSouth AsianSub978G=0.710T=0.290
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.634T=0.366
The Genome Aggregation DatabaseAfricanSub8708G=0.561T=0.439
The Genome Aggregation DatabaseAmericanSub838G=0.650T=0.350
The Genome Aggregation DatabaseEast AsianSub1606G=0.611T=0.389
The Genome Aggregation DatabaseEuropeSub18424G=0.647T=0.352
The Genome Aggregation DatabaseGlobalStudy-wide29878G=0.618T=0.381
The Genome Aggregation DatabaseOtherSub302G=0.500T=0.500
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.587T=0.412
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.633T=0.367
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs76832440.000345alcohol dependence20201924

eQTL of rs7683244 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr4:31966758RP11-734I18.1ENSG00000251129.1G>T1.3641e-16-32261Hypothalamus

meQTL of rs7683244 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr43201043832010482E06843680