SNP Detail Info-rs7685041

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0239 (7139/29808,GnomAD)
G==0205 (5991/29118,TOPMED)
G==0254 (1274/5008,1000G)
G==0201 (774/3854,ALSPAC)
G==0203 (753/3708,TWINSUK)

Position: chr4:58854266 (GRCh38.p7) (4q13.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.58854266G>A
GRCh37.p13 chr 4	NC_000004.11:g.59720431G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.179	A=0.821
1000Genomes	American	Sub	694	G=0.260	A=0.740
1000Genomes	East Asian	Sub	1008	G=0.398	A=0.602
1000Genomes	Europe	Sub	1006	G=0.241	A=0.759
1000Genomes	Global	Study-wide	5008	G=0.254	A=0.746
1000Genomes	South Asian	Sub	978	G=0.220	A=0.780
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.201	A=0.799
The Genome Aggregation Database	African	Sub	8678	G=0.184	A=0.816
The Genome Aggregation Database	American	Sub	832	G=0.230	A=0.770
The Genome Aggregation Database	East Asian	Sub	1570	G=0.429	A=0.571
The Genome Aggregation Database	Europe	Sub	18426	G=0.249	A=0.750
The Genome Aggregation Database	Global	Study-wide	29808	G=0.239	A=0.760
The Genome Aggregation Database	Other	Sub	302	G=0.250	A=0.750
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.205	A=0.794
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.203	A=0.797

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs7685041	0.0006	alcohol dependence(early age of onset)	20201924
rs7685041	0.00095	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs7685041