rs7685223

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0318 (9507/29900,GnomAD)
G==0320 (9325/29118,TOPMED)
G==0318 (1594/5008,1000G)
G==0293 (1129/3854,ALSPAC)
G==0291 (1078/3708,TWINSUK)
chr4:36660237 (GRCh38.p7) (4p14)
CD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.36660237G>A
GRCh37.p13 chr 4NC_000004.11:g.36661859G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.371A=0.629
1000GenomesAmericanSub694G=0.340A=0.660
1000GenomesEast AsianSub1008G=0.350A=0.650
1000GenomesEuropeSub1006G=0.276A=0.724
1000GenomesGlobalStudy-wide5008G=0.318A=0.682
1000GenomesSouth AsianSub978G=0.240A=0.760
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.293A=0.707
The Genome Aggregation DatabaseAfricanSub8688G=0.369A=0.631
The Genome Aggregation DatabaseAmericanSub836G=0.360A=0.640
The Genome Aggregation DatabaseEast AsianSub1614G=0.349A=0.651
The Genome Aggregation DatabaseEuropeSub18460G=0.288A=0.711
The Genome Aggregation DatabaseGlobalStudy-wide29900G=0.318A=0.682
The Genome Aggregation DatabaseOtherSub302G=0.350A=0.650
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.320A=0.679
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.291A=0.709
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs76852230.000339cocaine dependence23958962

eQTL of rs7685223 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7685223 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr43667788536678068E08116026
chr43667788536678068E08216026
chr43667812636678541E08216267