rs7692181

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0306 (9154/29890,GnomAD)
T=0267 (7795/29118,TOPMED)
T=0252 (1263/5008,1000G)
T=0349 (1346/3854,ALSPAC)
T=0362 (1341/3708,TWINSUK)
chr4:63635276 (GRCh38.p7) (4q13.1)
ND
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.63635276C>T
GRCh37.p13 chr 4NC_000004.11:g.64500994C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.874T=0.126
1000GenomesAmericanSub694C=0.780T=0.220
1000GenomesEast AsianSub1008C=0.746T=0.254
1000GenomesEuropeSub1006C=0.591T=0.409
1000GenomesGlobalStudy-wide5008C=0.748T=0.252
1000GenomesSouth AsianSub978C=0.720T=0.280
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.651T=0.349
The Genome Aggregation DatabaseAfricanSub8702C=0.835T=0.165
The Genome Aggregation DatabaseAmericanSub832C=0.760T=0.240
The Genome Aggregation DatabaseEast AsianSub1608C=0.762T=0.238
The Genome Aggregation DatabaseEuropeSub18446C=0.620T=0.380
The Genome Aggregation DatabaseGlobalStudy-wide29890C=0.693T=0.306
The Genome Aggregation DatabaseOtherSub302C=0.560T=0.440
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.732T=0.267
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.638T=0.362
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs76921817.63E-05nicotine smoking19268276

eQTL of rs7692181 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7692181 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr46448503264485731E070-15263
chr46448603864486300E070-14694
chr46448503264485731E081-15263
chr46448603864486300E081-14694
chr46448503264485731E082-15263
chr46448603864486300E082-14694