rs770182

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0343 (10276/29918,GnomAD)
G==0353 (10282/29118,TOPMED)
G==0323 (1618/5008,1000G)
G==0309 (1191/3854,ALSPAC)
G==0303 (1122/3708,TWINSUK)
chr5:107782439 (GRCh38.p7) (5q21.3)
AD
GWASdb2
2   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.107782439G>T
GRCh37.p13 chr 5NC_000005.9:g.107118140G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.413T=0.587
1000GenomesAmericanSub694G=0.280T=0.720
1000GenomesEast AsianSub1008G=0.187T=0.813
1000GenomesEuropeSub1006G=0.312T=0.688
1000GenomesGlobalStudy-wide5008G=0.323T=0.677
1000GenomesSouth AsianSub978G=0.380T=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.309T=0.691
The Genome Aggregation DatabaseAfricanSub8712G=0.379T=0.621
The Genome Aggregation DatabaseAmericanSub836G=0.310T=0.690
The Genome Aggregation DatabaseEast AsianSub1614G=0.209T=0.791
The Genome Aggregation DatabaseEuropeSub18456G=0.340T=0.659
The Genome Aggregation DatabaseGlobalStudy-wide29918G=0.343T=0.656
The Genome Aggregation DatabaseOtherSub300G=0.290T=0.710
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.353T=0.646
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.303T=0.697
PMID Title Author Journal
22072270Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.Wang KSJ Neural Transm (Vienna)
25043041Neuropsychosocial profiles of current and future adolescent alcohol misusers.Whelan RNature

P-Value

SNP ID p-value Traits Study
rs7701823.65E-06alcohol withdrawal symptoms22072270

eQTL of rs770182 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs770182 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5107140779107141147E07022639
chr5107141604107141709E07023464
chr5107142042107142355E07023902
chr5107144282107144943E07026142