rs770224

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0431 (12914/29936,GnomAD)
C=0434 (12637/29118,TOPMED)
C=0376 (1885/5008,1000G)
C=0452 (1741/3854,ALSPAC)
C=0470 (1742/3708,TWINSUK)
chr18:2533131 (GRCh38.p7) (18p11.32)
AD
GWASdb2
1   publication(s)
See rs on genome
43 Enhancers around
27 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.2533131T>C
GRCh37.p13 chr 18NC_000018.9:g.2533130T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.548C=0.452
1000GenomesAmericanSub694T=0.700C=0.300
1000GenomesEast AsianSub1008T=0.818C=0.182
1000GenomesEuropeSub1006T=0.534C=0.466
1000GenomesGlobalStudy-wide5008T=0.624C=0.376
1000GenomesSouth AsianSub978T=0.560C=0.440
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.548C=0.452
The Genome Aggregation DatabaseAfricanSub8708T=0.553C=0.447
The Genome Aggregation DatabaseAmericanSub834T=0.710C=0.290
The Genome Aggregation DatabaseEast AsianSub1616T=0.808C=0.192
The Genome Aggregation DatabaseEuropeSub18478T=0.548C=0.451
The Genome Aggregation DatabaseGlobalStudy-wide29936T=0.568C=0.431
The Genome Aggregation DatabaseOtherSub300T=0.580C=0.420
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.566C=0.434
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.530C=0.470
PMID Title Author Journal

P-Value

SNP ID p-value Traits Study
rs7702242.12E-05alcoholismpha002893

eQTL of rs770224 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs770224 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1825382542538352E0675124
chr1825383802538572E0675250
chr1825696722569836E06736542
chr1825698942570033E06736764
chr1825382542538352E0685124
chr1825383802538572E0685250
chr1825696722569836E06836542
chr1825383802538572E0695250
chr1825696722569836E06936542
chr1825698942570033E06936764
chr1825105432510788E070-22342
chr1825689592569021E07035829
chr1825693082569358E07036178
chr1825694662569598E07036336
chr1825696722569836E07036542
chr1825698942570033E07036764
chr1825694662569598E07136336
chr1825696722569836E07136542
chr1825696722569836E07236542
chr1825698942570033E07236764
chr1825696722569836E07336542
chr1825698942570033E07336764
chr1825689592569021E07435829
chr1825693082569358E07436178
chr1825694662569598E07436336
chr1825696722569836E07436542
chr1825698942570033E07436764
chr1824832202483328E081-49802
chr1824833742483554E081-49576
chr1825104872510535E081-22595
chr1825105432510788E081-22342
chr1825689592569021E08135829
chr1825693082569358E08136178
chr1825694662569598E08136336
chr1825696722569836E08136542
chr1825698942570033E08136764
chr1824832202483328E082-49802
chr1824833742483554E082-49576
chr1825689592569021E08235829
chr1825693082569358E08236178
chr1825694662569598E08236336
chr1825696722569836E08236542
chr1825698942570033E08236764










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1825704722570555E06737342
chr1825706042572752E06737474
chr1825704722570555E06837342
chr1825706042572752E06837474
chr1825704722570555E06937342
chr1825706042572752E06937474
chr1825704722570555E07037342
chr1825706042572752E07037474
chr1825727962572922E07039666
chr1825735402573722E07040410
chr1825738192573908E07040689
chr1825704722570555E07137342
chr1825706042572752E07137474
chr1825704722570555E07237342
chr1825706042572752E07237474
chr1825704722570555E07337342
chr1825706042572752E07337474
chr1825704722570555E07437342
chr1825706042572752E07437474
chr1825704722570555E08137342
chr1825706042572752E08137474
chr1825727962572922E08139666
chr1825704722570555E08237342
chr1825706042572752E08237474
chr1825727962572922E08239666
chr1825735402573722E08240410
chr1825738192573908E08240689