rs7704911

Homo sapiens
C>T
ARL15 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0352 (10520/29888,GnomAD)
C==0377 (10986/29118,TOPMED)
C==0439 (2199/5008,1000G)
C==0291 (1122/3854,ALSPAC)
C==0282 (1047/3708,TWINSUK)
chr5:54291872 (GRCh38.p7) (5q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
26 Enhancers around
11 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.54291872C>T
GRCh37.p13 chr 5NC_000005.9:g.53587702C>T

Gene: ARL15, ADP ribosylation factor like GTPase 15(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ARL15 transcriptNM_019087.2:c.N/AIntron Variant
ARL15 transcript variant X1XM_011543498.2:c.N/AIntron Variant
ARL15 transcript variant X2XM_011543499.2:c.N/AIntron Variant
ARL15 transcript variant X3XM_011543500.2:c.N/AIntron Variant
ARL15 transcript variant X4XM_017009598.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.475T=0.525
1000GenomesAmericanSub694C=0.520T=0.480
1000GenomesEast AsianSub1008C=0.580T=0.420
1000GenomesEuropeSub1006C=0.282T=0.718
1000GenomesGlobalStudy-wide5008C=0.439T=0.561
1000GenomesSouth AsianSub978C=0.350T=0.650
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.291T=0.709
The Genome Aggregation DatabaseAfricanSub8694C=0.445T=0.555
The Genome Aggregation DatabaseAmericanSub836C=0.520T=0.480
The Genome Aggregation DatabaseEast AsianSub1608C=0.611T=0.389
The Genome Aggregation DatabaseEuropeSub18448C=0.280T=0.719
The Genome Aggregation DatabaseGlobalStudy-wide29888C=0.352T=0.648
The Genome Aggregation DatabaseOtherSub302C=0.220T=0.780
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.377T=0.622
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.282T=0.718
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs77049119.88E-06alcohol dependence (age at onset)24962325

eQTL of rs7704911 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7704911 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr55359219153592302E0674489
chr55359230553592489E0674603
chr55360474653604828E06717044
chr55359156353591979E0683861
chr55359219153592302E0684489
chr55359230553592489E0684603
chr55357394153574185E069-13517
chr55357422253574433E069-13269
chr55360335753603465E07015655
chr55360351753603786E07015815
chr55360440353604546E07016701
chr55360474653604828E07117044
chr55357394153574185E072-13517
chr55357422253574433E072-13269
chr55357444553574505E072-13197
chr55357422253574433E074-13269
chr55357444553574505E074-13197
chr55359119253591246E0743490
chr55359156353591979E0743861
chr55359219153592302E0744489
chr55359230553592489E0744603
chr55360351753603786E08115815
chr55360427953604329E08116577
chr55360440353604546E08116701
chr55360474653604828E08117044
chr55360803253608085E08120330








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr55360503053607991E06717328
chr55360503053607991E06817328
chr55360503053607991E06917328
chr55360503053607991E07017328
chr55355060653550896E071-36806
chr55360503053607991E07117328
chr55360503053607991E07217328
chr55360503053607991E07317328
chr55360503053607991E07417328
chr55360503053607991E08117328
chr55360503053607991E08217328