rs7707639

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0095 (2851/29970,GnomAD)
A=0123 (3605/29118,TOPMED)
A=0111 (555/5008,1000G)
A=0046 (179/3854,ALSPAC)
A=0045 (168/3708,TWINSUK)
chr5:55715135 (GRCh38.p7) (5q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.55715135G>A
GRCh37.p13 chr 5NC_000005.9:g.55010963G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.730A=0.270
1000GenomesAmericanSub694G=0.960A=0.040
1000GenomesEast AsianSub1008G=0.962A=0.038
1000GenomesEuropeSub1006G=0.956A=0.044
1000GenomesGlobalStudy-wide5008G=0.889A=0.111
1000GenomesSouth AsianSub978G=0.910A=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.954A=0.046
The Genome Aggregation DatabaseAfricanSub8718G=0.774A=0.226
The Genome Aggregation DatabaseAmericanSub838G=0.950A=0.050
The Genome Aggregation DatabaseEast AsianSub1616G=0.960A=0.040
The Genome Aggregation DatabaseEuropeSub18496G=0.960A=0.039
The Genome Aggregation DatabaseGlobalStudy-wide29970G=0.904A=0.095
The Genome Aggregation DatabaseOtherSub302G=0.880A=0.120
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.876A=0.123
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.955A=0.045
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs77076390.000504alcohol dependence20201924

eQTL of rs7707639 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7707639 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr55496792654968020E067-42943
chr55496839854969030E067-41933
chr55497099554971215E067-39748
chr55497131754971465E067-39498
chr55498703754988015E067-22948
chr55496792654968020E068-42943
chr55497561454975700E068-35263
chr55497589254975948E068-35015
chr55497730654977409E068-33554
chr55498703754988015E068-22948
chr55496792654968020E069-42943
chr55496839854969030E069-41933
chr55498578354985865E069-25098
chr55498703754988015E069-22948
chr55496792654968020E071-42943
chr55496839854969030E071-41933
chr55496915254969221E071-41742
chr55497561454975700E071-35263
chr55497589254975948E071-35015
chr55497616854976411E071-34552
chr55497650754976846E071-34117
chr55497730654977409E071-33554
chr55497768554977799E071-33164
chr55497804554978106E071-32857
chr55498578354985865E071-25098
chr55498614754986649E071-24314
chr55498703754988015E071-22948
chr55499746854997554E071-13409
chr55499771254997833E071-13130
chr55496792654968020E072-42943
chr55496839854969030E072-41933
chr55497616854976411E072-34552
chr55498703754988015E072-22948
chr55496839854969030E073-41933
chr55497616854976411E073-34552
chr55497650754976846E073-34117
chr55497730654977409E073-33554
chr55496792654968020E074-42943
chr55496839854969030E074-41933
chr55496915254969221E074-41742
chr55496939554969475E074-41488
chr55497031954970447E074-40516
chr55498578354985865E074-25098
chr55498614754986649E074-24314
chr55498703754988015E074-22948
chr55502024555020345E0749282







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr55500720455008870E067-2093
chr55500720455008870E068-2093
chr55500720455008870E069-2093
chr55500720455008870E070-2093
chr55500720455008870E071-2093
chr55500720455008870E072-2093
chr55500720455008870E073-2093
chr55500720455008870E074-2093
chr55500720455008870E081-2093
chr55500720455008870E082-2093