SNP Detail Info-rs7710841

Organism: Homo sapiens

Alleles: C>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

T=0393 (11745/29876,GnomAD)
T=0422 (12309/29118,TOPMED)
T=0412 (2061/5008,1000G)
T=0362 (1397/3854,ALSPAC)
T=0362 (1341/3708,TWINSUK)

Position: chr5:50349986 (GRCh38.p7) (5q11.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.50349986C>T
GRCh37.p13 chr 5	NC_000005.9:g.49645820C>T

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.491	T=0.509
1000Genomes	American	Sub	694	C=0.670	T=0.330
1000Genomes	East Asian	Sub	1008	C=0.527	T=0.473
1000Genomes	Europe	Sub	1006	C=0.669	T=0.331
1000Genomes	Global	Study-wide	5008	C=0.588	T=0.412
1000Genomes	South Asian	Sub	978	C=0.640	T=0.360
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.638	T=0.362
The Genome Aggregation Database	African	Sub	8704	C=0.478	T=0.522
The Genome Aggregation Database	American	Sub	836	C=0.660	T=0.340
The Genome Aggregation Database	East Asian	Sub	1572	C=0.482	T=0.518
The Genome Aggregation Database	Europe	Sub	18464	C=0.674	T=0.325
The Genome Aggregation Database	Global	Study-wide	29876	C=0.606	T=0.393
The Genome Aggregation Database	Other	Sub	300	C=0.680	T=0.320
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.577	T=0.422
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.638	T=0.362

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs7710841	0.0000906	alcoholism	pha002891
rs7710841	0.0000906	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
cg15950743	chr5:49708521	EMB	-0.08883063749868	1.0654e-35

rs7710841