rs77114337

Homo sapiens
T>C
SULT1B1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0046 (1378/29976,GnomAD)
C=0045 (1317/29118,TOPMED)
C=0056 (278/5008,1000G)
C=0064 (245/3854,ALSPAC)
C=0059 (220/3708,TWINSUK)
chr4:69758944 (GRCh38.p7) (4q13.3)
ND
GWASCatalog
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.69758944T>C
GRCh37.p13 chr 4NC_000004.11:g.70624662T>C

Gene: SULT1B1, sulfotransferase family 1B member 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
SULT1B1 transcriptNM_014465.3:c.N/AIntron Variant
SULT1B1 transcript variant X1XM_005265676.3:c.N/AIntron Variant
SULT1B1 transcript variant X2XM_005265677.3:c.N/AIntron Variant
SULT1B1 transcript variant X3XM_005265678.3:c.N/AIntron Variant
SULT1B1 transcript variant X4XM_011531873.2:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.995C=0.005
1000GenomesAmericanSub694T=0.960C=0.040
1000GenomesEast AsianSub1008T=0.884C=0.116
1000GenomesEuropeSub1006T=0.939C=0.061
1000GenomesGlobalStudy-wide5008T=0.944C=0.056
1000GenomesSouth AsianSub978T=0.940C=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.936C=0.064
The Genome Aggregation DatabaseAfricanSub8730T=0.989C=0.011
The Genome Aggregation DatabaseAmericanSub838T=0.950C=0.050
The Genome Aggregation DatabaseEast AsianSub1616T=0.912C=0.088
The Genome Aggregation DatabaseEuropeSub18490T=0.941C=0.058
The Genome Aggregation DatabaseGlobalStudy-wide29976T=0.954C=0.046
The Genome Aggregation DatabaseOtherSub302T=0.970C=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.954C=0.045
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.941C=0.059
PMID Title Author Journal
28440896Genome-wide meta-analysis identifies a novel susceptibility signal at CACNA2D3 for nicotine dependence.Yin XAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs771143374E-06nicotine dependence28440896

eQTL of rs77114337 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs77114337 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.