rs7714594

Homo sapiens
C>A
LOC107986418 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0161 (4830/29924,GnomAD)
A=0193 (5620/29118,TOPMED)
A=0159 (611/3854,ALSPAC)
A=0153 (568/3708,TWINSUK)
chr5:63358855 (GRCh38.p7) (5q12.1)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.63358855C>A
GRCh37.p13 chr 5NC_000005.9:g.62654682C>A

Gene: LOC107986418, uncharacterized LOC107986418(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107986418 transcriptXR_001742680.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.841A=0.159
The Genome Aggregation DatabaseAfricanSub8720C=0.756A=0.244
The Genome Aggregation DatabaseAmericanSub836C=0.860A=0.140
The Genome Aggregation DatabaseEast AsianSub1604C=0.999A=0.001
The Genome Aggregation DatabaseEuropeSub18462C=0.864A=0.135
The Genome Aggregation DatabaseGlobalStudy-wide29924C=0.838A=0.161
The Genome Aggregation DatabaseOtherSub302C=0.740A=0.260
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.807A=0.193
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.847A=0.153
PMID Title Author Journal
22488850Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.Zuo LAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs77145946.1E-07alcohol and nictotine co-dependence22488850

eQTL of rs7714594 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7714594 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.