rs7715840

Homo sapiens
A>C
LOC645261 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0354 (10539/29770,GnomAD)
A==0388 (11304/29118,TOPMED)
A==0283 (1415/5008,1000G)
A==0232 (896/3854,ALSPAC)
A==0245 (909/3708,TWINSUK)
chr5:87055061 (GRCh38.p7) (5q14.3)
AD
GWASdb2
1   publication(s)
See rs on genome
12 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.87055061A>C
GRCh37.p13 chr 5NC_000005.9:g.86350878A>C

Gene: LOC645261, uncharacterized LOC645261(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC645261 transcriptXR_948538.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.667C=0.333
1000GenomesAmericanSub694A=0.150C=0.850
1000GenomesEast AsianSub1008A=0.042C=0.958
1000GenomesEuropeSub1006A=0.249C=0.751
1000GenomesGlobalStudy-wide5008A=0.283C=0.717
1000GenomesSouth AsianSub978A=0.140C=0.860
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.232C=0.768
The Genome Aggregation DatabaseAfricanSub8682A=0.609C=0.391
The Genome Aggregation DatabaseAmericanSub828A=0.180C=0.820
The Genome Aggregation DatabaseEast AsianSub1610A=0.050C=0.950
The Genome Aggregation DatabaseEuropeSub18348A=0.268C=0.732
The Genome Aggregation DatabaseGlobalStudy-wide29770A=0.354C=0.646
The Genome Aggregation DatabaseOtherSub302A=0.330C=0.670
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.388C=0.611
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.245C=0.755
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs77158404.3E-05alcoholism (heaviness of drinking)21529783

eQTL of rs7715840 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7715840 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr58631548886316412E067-34466
chr58631652986316591E067-34287
chr58631548886316412E068-34466
chr58631652986316591E068-34287
chr58631548886316412E069-34466
chr58631652986316591E069-34287
chr58631548886316412E070-34466
chr58631548886316412E071-34466
chr58631652986316591E071-34287
chr58637691686377244E07126038
chr58631548886316412E074-34466
chr58631652986316591E074-34287