rs7722750

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0065 (1959/29938,GnomAD)
T=0094 (2757/29118,TOPMED)
T=0077 (384/5008,1000G)
T=0019 (73/3854,ALSPAC)
T=0022 (80/3708,TWINSUK)
chr5:91865513 (GRCh38.p7) (5q14.3)
AD
GWASdb2
1   publication(s)
See rs on genome
27 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.91865513G>T
GRCh37.p13 chr 5NC_000005.9:g.91161330G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.799T=0.201
1000GenomesAmericanSub694G=0.970T=0.030
1000GenomesEast AsianSub1008G=0.982T=0.018
1000GenomesEuropeSub1006G=0.983T=0.017
1000GenomesGlobalStudy-wide5008G=0.923T=0.077
1000GenomesSouth AsianSub978G=0.940T=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.981T=0.019
The Genome Aggregation DatabaseAfricanSub8700G=0.813T=0.187
The Genome Aggregation DatabaseAmericanSub838G=0.980T=0.020
The Genome Aggregation DatabaseEast AsianSub1616G=0.986T=0.014
The Genome Aggregation DatabaseEuropeSub18482G=0.984T=0.015
The Genome Aggregation DatabaseGlobalStudy-wide29938G=0.934T=0.065
The Genome Aggregation DatabaseOtherSub302G=0.980T=0.020
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.905T=0.094
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.978T=0.022
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs77227500.0005alcohol dependence20201924

eQTL of rs7722750 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7722750 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr59116060491160668E070-662
chr59116088791160972E070-358
chr59116113491161239E070-91
chr59112000491120070E081-41260
chr59112022391120571E081-40759
chr59112061391120741E081-40589
chr59113483091135621E081-25709
chr59113566791136055E081-25275
chr59113619491136284E081-25046
chr59113639091136500E081-24830
chr59113650291136876E081-24454
chr59113707991137129E081-24201
chr59113749491137695E081-23635
chr59116060491160668E081-662
chr59116088791160972E081-358
chr59118143191181859E08120101
chr59119386691194163E08132536
chr59119472691195097E08133396
chr59113483091135621E082-25709
chr59113566791136055E082-25275
chr59113619491136284E082-25046
chr59113639091136500E082-24830
chr59113650291136876E082-24454
chr59113707991137129E082-24201
chr59118143191181859E08220101
chr59118192591181993E08220595
chr59119386691194163E08232536