SNP Detail Info-rs7731099

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0268 (8003/29836,GnomAD)
A=0316 (9228/29118,TOPMED)
A=0249 (1247/5008,1000G)
A=0207 (796/3854,ALSPAC)
A=0206 (762/3708,TWINSUK)

Position: chr5:45037924 (GRCh38.p7) (5p12)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.45037924G>A
GRCh37.p13 chr 5	NC_000005.9:g.45038026G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.563	A=0.437
1000Genomes	American	Sub	694	G=0.710	A=0.290
1000Genomes	East Asian	Sub	1008	G=0.933	A=0.067
1000Genomes	Europe	Sub	1006	G=0.787	A=0.213
1000Genomes	Global	Study-wide	5008	G=0.751	A=0.249
1000Genomes	South Asian	Sub	978	G=0.810	A=0.190
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.793	A=0.207
The Genome Aggregation Database	African	Sub	8702	G=0.566	A=0.434
The Genome Aggregation Database	American	Sub	834	G=0.730	A=0.270
The Genome Aggregation Database	East Asian	Sub	1584	G=0.929	A=0.071
The Genome Aggregation Database	Europe	Sub	18414	G=0.793	A=0.206
The Genome Aggregation Database	Global	Study-wide	29836	G=0.731	A=0.268
The Genome Aggregation Database	Other	Sub	302	G=0.690	A=0.310
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.683	A=0.316
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.794	A=0.206

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs7731099	0.000243	alcohol consumption (maxi-drinks)	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs7731099