rs7733888

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0130 (3905/29976,GnomAD)
C=0172 (5026/29118,TOPMED)
C=0130 (652/5008,1000G)
C=0070 (271/3854,ALSPAC)
C=0060 (221/3708,TWINSUK)
chr5:86648119 (GRCh38.p7) (5q14.3)
AD
GWASdb2
1   publication(s)
See rs on genome
14 Enhancers around
26 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.86648119T>C
GRCh37.p13 chr 5NC_000005.9:g.85943936T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.672C=0.328
1000GenomesAmericanSub694T=0.900C=0.100
1000GenomesEast AsianSub1008T=0.952C=0.048
1000GenomesEuropeSub1006T=0.942C=0.058
1000GenomesGlobalStudy-wide5008T=0.870C=0.130
1000GenomesSouth AsianSub978T=0.950C=0.050
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.930C=0.070
The Genome Aggregation DatabaseAfricanSub8722T=0.690C=0.310
The Genome Aggregation DatabaseAmericanSub838T=0.910C=0.090
The Genome Aggregation DatabaseEast AsianSub1622T=0.958C=0.042
The Genome Aggregation DatabaseEuropeSub18492T=0.943C=0.056
The Genome Aggregation DatabaseGlobalStudy-wide29976T=0.869C=0.130
The Genome Aggregation DatabaseOtherSub302T=0.950C=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.827C=0.172
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.940C=0.060
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs77338880.00025alcohol dependence20201924

eQTL of rs7733888 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7733888 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr58591525785915330E068-28606
chr58597528985975747E06931353
chr58591525785915330E070-28606
chr58591569485915776E070-28160
chr58591597585916015E070-27921
chr58591525785915330E071-28606
chr58591569485915776E071-28160
chr58597528985975747E07131353
chr58591525785915330E073-28606
chr58591569485915776E073-28160
chr58591525785915330E074-28606
chr58591569485915776E074-28160
chr58591525785915330E081-28606
chr58591597585916015E082-27921








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr58591319685913264E067-30672
chr58591328285914577E067-29359
chr58591482485915172E067-28764
chr58591319685913264E068-30672
chr58591328285914577E068-29359
chr58591482485915172E068-28764
chr58591319685913264E069-30672
chr58591328285914577E069-29359
chr58591482485915172E069-28764
chr58591328285914577E070-29359
chr58591482485915172E070-28764
chr58591319685913264E071-30672
chr58591328285914577E071-29359
chr58591319685913264E072-30672
chr58591328285914577E072-29359
chr58591482485915172E072-28764
chr58591328285914577E073-29359
chr58591482485915172E073-28764
chr58591319685913264E074-30672
chr58591328285914577E074-29359
chr58591482485915172E074-28764
chr58591319685913264E081-30672
chr58591328285914577E081-29359
chr58591482485915172E081-28764
chr58591328285914577E082-29359
chr58591482485915172E082-28764