rs7736676

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0318 (9486/29820,GnomAD)
A==0260 (7575/29118,TOPMED)
A==0398 (1991/5008,1000G)
A==0374 (1442/3854,ALSPAC)
A==0372 (1378/3708,TWINSUK)
chr5:117194234 (GRCh38.p7) (5q23.1)
CD
GWASdb2
1   publication(s)
See rs on genome
28 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.117194234A>G
GRCh37.p13 chr 5NC_000005.9:g.116529930A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.059G=0.941
1000GenomesAmericanSub694A=0.370G=0.630
1000GenomesEast AsianSub1008A=0.736G=0.264
1000GenomesEuropeSub1006A=0.364G=0.636
1000GenomesGlobalStudy-wide5008A=0.398G=0.602
1000GenomesSouth AsianSub978A=0.560G=0.440
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.374G=0.626
The Genome Aggregation DatabaseAfricanSub8682A=0.097G=0.903
The Genome Aggregation DatabaseAmericanSub834A=0.370G=0.630
The Genome Aggregation DatabaseEast AsianSub1572A=0.728G=0.272
The Genome Aggregation DatabaseEuropeSub18432A=0.384G=0.615
The Genome Aggregation DatabaseGlobalStudy-wide29820A=0.318G=0.681
The Genome Aggregation DatabaseOtherSub300A=0.340G=0.660
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.260G=0.739
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.372G=0.628
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs77366760.000201cocaine dependence,AA23958962
rs77366760.000983cocaine dependence23958962

eQTL of rs7736676 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7736676 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5116525642116525708E067-4222
chr5116497497116497610E068-32320
chr5116540747116540856E06810817
chr5116540957116541035E06811027
chr5116497497116497610E069-32320
chr5116497629116498003E069-31927
chr5116540747116540856E06910817
chr5116540957116541035E06911027
chr5116497497116497610E071-32320
chr5116497629116498003E071-31927
chr5116540747116540856E07110817
chr5116497497116497610E072-32320
chr5116497629116498003E072-31927
chr5116500909116500986E072-28944
chr5116537264116537638E0727334
chr5116540747116540856E07210817
chr5116540747116540856E07310817
chr5116540957116541035E07311027
chr5116541110116541314E07311180
chr5116541340116541486E07311410
chr5116497497116497610E074-32320
chr5116497629116498003E074-31927
chr5116500909116500986E074-28944
chr5116525642116525708E074-4222
chr5116540747116540856E07410817
chr5116540957116541035E07411027
chr5116541110116541314E07411180
chr5116541340116541486E07411410