rs7749514

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0080 (2410/29972,GnomAD)
T=0069 (2034/29118,TOPMED)
T=0061 (307/5008,1000G)
T=0089 (344/3854,ALSPAC)
T=0100 (371/3708,TWINSUK)
chr6:2524712 (GRCh38.p7) (6p25.2)
AD
GWASdb2
1   publication(s)
See rs on genome
46 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.2524712C>T
GRCh37.p13 chr 6NC_000006.11:g.2524946C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.926T=0.074
1000GenomesAmericanSub694C=0.950T=0.050
1000GenomesEast AsianSub1008C=0.999T=0.001
1000GenomesEuropeSub1006C=0.905T=0.095
1000GenomesGlobalStudy-wide5008C=0.939T=0.061
1000GenomesSouth AsianSub978C=0.920T=0.080
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.911T=0.089
The Genome Aggregation DatabaseAfricanSub8720C=0.925T=0.075
The Genome Aggregation DatabaseAmericanSub838C=0.960T=0.040
The Genome Aggregation DatabaseEast AsianSub1622C=0.999T=0.001
The Genome Aggregation DatabaseEuropeSub18490C=0.907T=0.092
The Genome Aggregation DatabaseGlobalStudy-wide29972C=0.919T=0.080
The Genome Aggregation DatabaseOtherSub302C=0.940T=0.060
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.930T=0.069
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.900T=0.100
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs77495140.000742alcohol dependence21314694

eQTL of rs7749514 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7749514 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr624802432480311E067-44635
chr624804832480666E067-44280
chr624807782480882E067-44064
chr624809542481301E067-43645
chr624986452498772E067-26174
chr624802432480311E068-44635
chr624804832480666E068-44280
chr624807782480882E068-44064
chr624809542481301E068-43645
chr624802432480311E069-44635
chr624804832480666E069-44280
chr624807782480882E069-44064
chr624809542481301E069-43645
chr624813452481406E069-43540
chr624986452498772E069-26174
chr625612452561345E06936299
chr625615602561702E06936614
chr625617362561835E06936790
chr625069792507300E070-17646
chr625073302507668E070-17278
chr625077942508192E070-16754
chr624802432480311E071-44635
chr624804832480666E071-44280
chr624807782480882E071-44064
chr624809542481301E071-43645
chr624813452481406E071-43540
chr624804832480666E072-44280
chr624807782480882E072-44064
chr624809542481301E072-43645
chr624986452498772E072-26174
chr625612452561345E07236299
chr624804832480666E073-44280
chr624807782480882E073-44064
chr624809542481301E073-43645
chr624986452498772E073-26174
chr624802432480311E074-44635
chr624804832480666E074-44280
chr624807782480882E074-44064
chr624809542481301E074-43645
chr624813452481406E074-43540
chr624914862491536E081-33410
chr624915742491701E081-33245
chr624932822493544E081-31402
chr624981752498223E081-26723
chr625059442506119E081-18827
chr624986452498772E082-26174