rs7753810

Homo sapiens
T>G
UST : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0334 (10008/29900,GnomAD)
G=0368 (10739/29118,TOPMED)
G=0312 (1561/5008,1000G)
G=0304 (1173/3854,ALSPAC)
G=0304 (1127/3708,TWINSUK)
chr6:148791620 (GRCh38.p7) (6q25.1)
ND
GWASdb2
1   publication(s)
See rs on genome
112 Enhancers around
8 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.148791620T>G
GRCh37.p13 chr 6NC_000006.11:g.149112756T>G

Gene: UST, uronyl 2-sulfotransferase(plus strand)

Molecule type Change Amino acid[Codon] SO Term
UST transcriptNM_005715.2:c.N/AIntron Variant
UST transcript variant X2XM_011535378.2:c.N/AIntron Variant
UST transcript variant X3XM_017010152.1:c.N/AIntron Variant
UST transcript variant X1XR_001743088.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.521G=0.479
1000GenomesAmericanSub694T=0.630G=0.370
1000GenomesEast AsianSub1008T=0.877G=0.123
1000GenomesEuropeSub1006T=0.688G=0.312
1000GenomesGlobalStudy-wide5008T=0.688G=0.312
1000GenomesSouth AsianSub978T=0.760G=0.240
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.696G=0.304
The Genome Aggregation DatabaseAfricanSub8690T=0.520G=0.480
The Genome Aggregation DatabaseAmericanSub834T=0.680G=0.320
The Genome Aggregation DatabaseEast AsianSub1618T=0.861G=0.139
The Genome Aggregation DatabaseEuropeSub18456T=0.713G=0.286
The Genome Aggregation DatabaseGlobalStudy-wide29900T=0.665G=0.334
The Genome Aggregation DatabaseOtherSub302T=0.800G=0.200
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.631G=0.368
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.696G=0.304
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs77538100.000255nicotine dependence17158188

eQTL of rs7753810 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7753810 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6149066960149067052E067-45704
chr6149077752149077849E067-34907
chr6149077915149078070E067-34686
chr6149078077149078188E067-34568
chr6149078275149078411E067-34345
chr6149078464149078514E067-34242
chr6149078730149078780E067-33976
chr6149078800149078857E067-33899
chr6149078937149080403E067-32353
chr6149078077149078188E068-34568
chr6149081002149083426E068-29330
chr6149083429149083622E068-29134
chr6149111189149111450E068-1306
chr6149111673149111839E068-917
chr6149112636149112768E0680
chr6149120847149121011E0688091
chr6149121574149121714E0688818
chr6149078937149080403E069-32353
chr6149081002149083426E069-29330
chr6149083429149083622E069-29134
chr6149092014149092068E069-20688
chr6149112636149112768E0690
chr6149070056149070537E070-42219
chr6149070583149070633E070-42123
chr6149081002149083426E070-29330
chr6149083429149083622E070-29134
chr6149078937149080403E071-32353
chr6149081002149083426E071-29330
chr6149083429149083622E071-29134
chr6149097175149098407E071-14349
chr6149078077149078188E072-34568
chr6149078937149080403E072-32353
chr6149081002149083426E072-29330
chr6149086937149087248E072-25508
chr6149087307149087526E072-25230
chr6149077752149077849E073-34907
chr6149077915149078070E073-34686
chr6149078077149078188E073-34568
chr6149081002149083426E073-29330
chr6149083429149083622E073-29134
chr6149087307149087526E073-25230
chr6149087586149087801E073-24955
chr6149066960149067052E074-45704
chr6149081002149083426E074-29330
chr6149097175149098407E074-14349
chr6149112636149112768E0740
chr6149112824149113205E07468
chr6149120494149120628E0747738
chr6149120725149120789E0747969
chr6149120847149121011E0748091
chr6149121574149121714E0748818
chr6149070056149070537E081-42219
chr6149070583149070633E081-42123
chr6149070651149070747E081-42009
chr6149070880149070954E081-41802
chr6149071463149071513E081-41243
chr6149071532149071585E081-41171
chr6149071639149071689E081-41067
chr6149071850149071913E081-40843
chr6149071952149072310E081-40446
chr6149072312149073765E081-38991
chr6149077915149078070E081-34686
chr6149078077149078188E081-34568
chr6149078275149078411E081-34345
chr6149078464149078514E081-34242
chr6149078730149078780E081-33976
chr6149078800149078857E081-33899
chr6149078937149080403E081-32353
chr6149080632149080982E081-31774
chr6149081002149083426E081-29330
chr6149083429149083622E081-29134
chr6149083803149084095E081-28661
chr6149084255149084311E081-28445
chr6149089921149090318E081-22438
chr6149090396149090475E081-22281
chr6149090533149090573E081-22183
chr6149090624149090709E081-22047
chr6149090737149090958E081-21798
chr6149090990149091113E081-21643
chr6149091378149091428E081-21328
chr6149091450149091999E081-20757
chr6149092014149092068E081-20688
chr6149092290149092914E081-19842
chr6149092997149093073E081-19683
chr6149148140149148317E08135384
chr6149148616149149362E08135860
chr6149149615149149777E08136859
chr6149150073149150156E08137317
chr6149150325149150460E08137569
chr6149156704149156979E08143948
chr6149157032149157850E08144276
chr6149070056149070537E082-42219
chr6149070583149070633E082-42123
chr6149071850149071913E082-40843
chr6149071952149072310E082-40446
chr6149078275149078411E082-34345
chr6149078464149078514E082-34242
chr6149078730149078780E082-33976
chr6149078800149078857E082-33899
chr6149078937149080403E082-32353
chr6149081002149083426E082-29330
chr6149083429149083622E082-29134
chr6149089921149090318E082-22438
chr6149090396149090475E082-22281
chr6149090533149090573E082-22183
chr6149090624149090709E082-22047
chr6149090737149090958E082-21798
chr6149090990149091113E082-21643
chr6149091378149091428E082-21328
chr6149091450149091999E082-20757
chr6149092014149092068E082-20688
chr6149092290149092914E082-19842










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6149067065149070055E067-42701
chr6149067065149070055E068-42701
chr6149067065149070055E069-42701
chr6149067065149070055E071-42701
chr6149067065149070055E072-42701
chr6149067065149070055E073-42701
chr6149067065149070055E074-42701
chr6149067065149070055E082-42701