rs7761213

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0331 (9924/29918,GnomAD)
T==0326 (9510/29118,TOPMED)
T==0337 (1687/5008,1000G)
T==0327 (1261/3854,ALSPAC)
T==0317 (1176/3708,TWINSUK)
chr6:24028175 (GRCh38.p7) (6p22.3)
AD
GWASdb2
3   publication(s)
See rs on genome
35 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.24028175T>C
GRCh37.p13 chr 6NC_000006.11:g.24028403T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.362C=0.638
1000GenomesAmericanSub694T=0.250C=0.750
1000GenomesEast AsianSub1008T=0.304C=0.696
1000GenomesEuropeSub1006T=0.345C=0.655
1000GenomesGlobalStudy-wide5008T=0.337C=0.663
1000GenomesSouth AsianSub978T=0.390C=0.610
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.327C=0.673
The Genome Aggregation DatabaseAfricanSub8716T=0.354C=0.646
The Genome Aggregation DatabaseAmericanSub834T=0.220C=0.780
The Genome Aggregation DatabaseEast AsianSub1616T=0.270C=0.730
The Genome Aggregation DatabaseEuropeSub18452T=0.330C=0.670
The Genome Aggregation DatabaseGlobalStudy-wide29918T=0.331C=0.668
The Genome Aggregation DatabaseOtherSub300T=0.410C=0.590
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.326C=0.673
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.317C=0.683
PMID Title Author Journal
22209813Sparse reduced-rank regression detects genetic associations with voxel-wise longitudinal phenotypes in Alzheimer's disease.Vounou MNeuroimage
24692236Novel QTL at chromosome 6p22 for alcohol consumption: Implications for the genetic liability of alcohol use disorders.Kos MZAm J Med Genet B Neuropsychiatr Genet
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs77612130.000338alcohol consumption (maxi-drinks)24277619

eQTL of rs7761213 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7761213 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr62405336924053757E06724966
chr62405288924053253E06824486
chr62405336924053757E06824966
chr62405288924053253E06924486
chr62405336924053757E06924966
chr62400796524008033E070-20370
chr62400810924008180E070-20223
chr62400822524008295E070-20108
chr62400939524009528E070-18875
chr62400962624010119E070-18284
chr62401019424010291E070-18112
chr62401073324010777E070-17626
chr62405256424052722E07024161
chr62405288924053253E07024486
chr62405336924053757E07024966
chr62406860424068654E07040201
chr62406917524069229E07040772
chr62406935024069400E07040947
chr62406956824069624E07041165
chr62406964424069815E07041241
chr62406987224070030E07041469
chr62407011924070222E07041716
chr62407231024072409E07043907
chr62405288924053253E07124486
chr62405336924053757E07124966
chr62405288924053253E07224486
chr62405336924053757E07224966
chr62405288924053253E07424486
chr62405336924053757E07424966
chr62405288924053253E08124486
chr62405336924053757E08124966
chr62400962624010119E082-18284
chr62405256424052722E08224161
chr62405288924053253E08224486
chr62405336924053757E08224966