rs7772532

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0326 (9732/29818,GnomAD)
T==0331 (9644/29118,TOPMED)
T==0391 (1960/5008,1000G)
T==0322 (1242/3854,ALSPAC)
T==0314 (1164/3708,TWINSUK)
chr6:48990205 (GRCh38.p7) (6p12.3)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.48990205T>G
GRCh37.p13 chr 6NC_000006.11:g.48957842T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.295G=0.705
1000GenomesAmericanSub694T=0.540G=0.460
1000GenomesEast AsianSub1008T=0.496G=0.504
1000GenomesEuropeSub1006T=0.325G=0.675
1000GenomesGlobalStudy-wide5008T=0.391G=0.609
1000GenomesSouth AsianSub978T=0.380G=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.322G=0.678
The Genome Aggregation DatabaseAfricanSub8668T=0.284G=0.716
The Genome Aggregation DatabaseAmericanSub836T=0.570G=0.430
The Genome Aggregation DatabaseEast AsianSub1606T=0.511G=0.489
The Genome Aggregation DatabaseEuropeSub18406T=0.320G=0.679
The Genome Aggregation DatabaseGlobalStudy-wide29818T=0.326G=0.673
The Genome Aggregation DatabaseOtherSub302T=0.260G=0.740
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.331G=0.668
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.314G=0.686
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs77725320.00019alcohol dependence20201924

eQTL of rs7772532 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr6:48957842CENPQENSG00000031691.6T>G5.7279e-16-473249Frontal_Cortex_BA9
Chr6:48957842CENPQENSG00000031691.6T>G2.1548e-12-473249Cortex
Chr6:48957842C6orf141ENSG00000197261.7T>G3.4487e-9-560271Cerebellar_Hemisphere

meQTL of rs7772532 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr64896943048970063E07011588
chr64896943048970063E07411588
chr64896943048970063E08111588
chr64897012648970409E08112284