rs7775895

Homo sapiens
G>A / G>T
SOBP : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0161 (4848/29938,GnomAD)
A=0192 (961/5008,1000G)
A=0142 (548/3854,ALSPAC)
A=0143 (531/3708,TWINSUK)
chr6:107565318 (GRCh38.p7) (6q21)
AD
GWASdb2
1   publication(s)
See rs on genome
54 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.107565318G>A
GRCh38.p7 chr 6NC_000006.12:g.107565318G>T
GRCh37.p13 chr 6NC_000006.11:g.107886522G>A
GRCh37.p13 chr 6NC_000006.11:g.107886522G>T
SOBP RefSeqGeneNG_028200.1:g.80206G>A
SOBP RefSeqGeneNG_028200.1:g.80206G>T

Gene: SOBP, sine oculis binding protein homolog(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SOBP transcriptNM_018013.3:c.N/AIntron Variant
SOBP transcript variant X1XM_005267041.4:c.N/AIntron Variant
SOBP transcript variant X3XM_005267042.4:c.N/AIntron Variant
SOBP transcript variant X2XM_011535920.2:c.N/AIntron Variant
SOBP transcript variant X4XM_011535921.2:c.N/AIntron Variant
SOBP transcript variant X9XM_011535923.2:c.N/AIntron Variant
SOBP transcript variant X5XM_017010991.1:c.N/AIntron Variant
SOBP transcript variant X6XM_017010992.1:c.N/AIntron Variant
SOBP transcript variant X7XM_017010993.1:c.N/AIntron Variant
SOBP transcript variant X8XM_017010994.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.742A=0.258
1000GenomesAmericanSub694G=0.840A=0.160
1000GenomesEast AsianSub1008G=0.959A=0.041
1000GenomesEuropeSub1006G=0.861A=0.139
1000GenomesGlobalStudy-wide5008G=0.808A=0.192
1000GenomesSouth AsianSub978G=0.670A=0.330
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.858A=0.142
The Genome Aggregation DatabaseAfricanSub8710G=0.755T=0.000
The Genome Aggregation DatabaseAmericanSub836G=0.830T=0.00,
The Genome Aggregation DatabaseEast AsianSub1616G=0.971T=0.000
The Genome Aggregation DatabaseEuropeSub18474G=0.866T=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29938G=0.838T=0.000
The Genome Aggregation DatabaseOtherSub302G=0.810T=0.00,
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.857A=0.143
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs77758955.6E-05alcoholism (heaviness of drinking)21529783

eQTL of rs7775895 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7775895 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr62081103020811991E067-15208
chr62081642520816742E067-10457
chr62083408720834856E0676888
chr62083494920835164E0677750
chr62079227420792577E068-34622
chr62083408720834856E0686888
chr62086844920868499E06841250
chr62086858620869421E06841387
chr62081103020811991E069-15208
chr62083408720834856E0696888
chr62083494920835164E0697750
chr62086858620869421E06941387
chr62081040820810863E070-16336
chr62086540520865455E07038206
chr62086639420866571E07039195
chr62086697320867055E07039774
chr62086723320867424E07040034
chr62086763520867794E07040436
chr62087034720870448E07043148
chr62087085020870991E07043651
chr62087327220873434E07046073
chr62087351720873961E07046318
chr62087410320874321E07046904
chr62087560920875887E07048410
chr62087633520876620E07049136
chr62081103020811991E071-15208
chr62081642520816742E071-10457
chr62081824320818404E071-8795
chr62083098620831066E0713787
chr62083408720834856E0716888
chr62083494920835164E0717750
chr62086844920868499E07141250
chr62086858620869421E07141387
chr62081103020811991E072-15208
chr62083408720834856E0726888
chr62083494920835164E0727750
chr62083408720834856E0746888
chr62083494920835164E0747750
chr62086844920868499E07441250
chr62086858620869421E07441387
chr62081103020811991E081-15208
chr62086763520867794E08140436
chr62086844920868499E08141250
chr62086858620869421E08141387
chr62087560920875887E08148410
chr62087633520876620E08149136
chr62086639420866571E08239195
chr62086697320867055E08239774
chr62086723320867424E08240034
chr62086763520867794E08240436
chr62086844920868499E08241250
chr62086858620869421E08241387
chr62087034720870448E08243148
chr62087633520876620E08249136