rs7779286

Homo sapiens
A>G
LOC107986765 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0186 (5577/29964,GnomAD)
A==0164 (4785/29118,TOPMED)
A==0080 (402/5008,1000G)
A==0248 (956/3854,ALSPAC)
A==0260 (964/3708,TWINSUK)
chr7:7936612 (GRCh38.p7) (7p21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
94 Enhancers around
11 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.7936612A>G
GRCh37.p13 chr 7NC_000007.13:g.7976243A>G

Gene: LOC107986765, uncharacterized LOC107986765(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107986765 transcript variant X2XR_001745079.1:n.N/AIntron Variant
LOC107986765 transcript variant X1XR_001745078.1:n.N/AGenic Upstream Transcript Variant
LOC107986765 transcript variant X3XR_001745080.1:n.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.041G=0.959
1000GenomesAmericanSub694A=0.110G=0.890
1000GenomesEast AsianSub1008A=0.001G=0.999
1000GenomesEuropeSub1006A=0.230G=0.770
1000GenomesGlobalStudy-wide5008A=0.080G=0.920
1000GenomesSouth AsianSub978A=0.040G=0.960
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.248G=0.752
The Genome Aggregation DatabaseAfricanSub8730A=0.064G=0.936
The Genome Aggregation DatabaseAmericanSub838A=0.140G=0.860
The Genome Aggregation DatabaseEast AsianSub1612A=0.000G=1.000
The Genome Aggregation DatabaseEuropeSub18482A=0.259G=0.740
The Genome Aggregation DatabaseGlobalStudy-wide29964A=0.186G=0.813
The Genome Aggregation DatabaseOtherSub302A=0.330G=0.670
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.164G=0.835
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.260G=0.740
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs77792860.00078alcohol dependence20201924

eQTL of rs7779286 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7779286 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr780147538014811E06738510
chr780149148015039E06738671
chr780174418017720E06741198
chr779596277959715E068-16528
chr779597467959799E068-16444
chr779616217961734E068-14509
chr779617417961835E068-14408
chr779619327962329E068-13914
chr779627407962861E068-13382
chr779632587963338E068-12905
chr779633477963567E068-12676
chr779836067985268E0687363
chr780125128012593E06836269
chr780126528012756E06836409
chr780147538014811E06838510
chr780149148015039E06838671
chr780150888015141E06838845
chr779323057932355E069-43888
chr779617417961835E069-14408
chr779619327962329E069-13914
chr779624027962604E069-13639
chr779626227962695E069-13548
chr779627407962861E069-13382
chr779632587963338E069-12905
chr779633477963567E069-12676
chr779342987934383E070-41860
chr779345057934622E070-41621
chr779346467935135E070-41108
chr779352367935341E070-40902
chr779354147935652E070-40591
chr779598807960008E070-16235
chr779600887960458E070-15785
chr779605377960581E070-15662
chr779606187960719E070-15524
chr779608107960878E070-15365
chr779610467961112E070-15131
chr779616217961734E070-14509
chr779617417961835E070-14408
chr779619327962329E070-13914
chr779624027962604E070-13639
chr779626227962695E070-13548
chr779627407962861E070-13382
chr779632587963338E070-12905
chr779633477963567E070-12676
chr779636187963729E070-12514
chr779637457963896E070-12347
chr779639817964181E070-12062
chr780171068017193E07040863
chr780174418017720E07041198
chr780191548019299E07042911
chr780193378019483E07043094
chr780195598019625E07043316
chr780198988020085E07043655
chr779342987934383E071-41860
chr779616217961734E071-14509
chr779617417961835E071-14408
chr779619327962329E071-13914
chr779636187963729E071-12514
chr780125128012593E07136269
chr780126528012756E07136409
chr780129718013274E07136728
chr780133148013418E07137071
chr779323057932355E072-43888
chr779600887960458E072-15785
chr779605377960581E072-15662
chr779606187960719E072-15524
chr779608107960878E072-15365
chr779616217961734E072-14509
chr779617417961835E072-14408
chr779619327962329E072-13914
chr779624027962604E072-13639
chr780171068017193E07340863
chr779590047959554E074-16689
chr779596277959715E074-16528
chr779597467959799E074-16444
chr779598807960008E074-16235
chr779600887960458E074-15785
chr779605377960581E074-15662
chr779606187960719E074-15524
chr779608107960878E074-15365
chr779610467961112E074-15131
chr779613927961442E074-14801
chr779616217961734E074-14509
chr779617417961835E074-14408
chr779619327962329E074-13914
chr779636187963729E074-12514
chr780125128012593E07436269
chr780129718013274E07436728
chr779323057932355E081-43888
chr779332547933304E081-42939
chr780125128012593E08136269
chr780126528012756E08136409
chr780129718013274E08136728
chr780129718013274E08236728










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr780074838011594E06731240
chr780074838011594E06831240
chr780074838011594E06931240
chr780074838011594E07031240
chr780073268007470E07131083
chr780074838011594E07131240
chr780074838011594E07231240
chr780074838011594E07331240
chr780074838011594E07431240
chr780074838011594E08131240
chr780074838011594E08231240