rs7792486

Homo sapiens
T>A / T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0064 (1916/29950,GnomAD)
C=0055 (1622/29118,TOPMED)
C=0070 (349/5008,1000G)
chr7:50418611 (GRCh38.p7) (7p12.2)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.50418611T>A
GRCh38.p7 chr 7NC_000007.14:g.50418611T>C
GRCh37.p13 chr 7NC_000007.13:g.50486309T>A
GRCh37.p13 chr 7NC_000007.13:g.50486309T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.922C=0.078
1000GenomesAmericanSub694T=0.970C=0.030
1000GenomesEast AsianSub1008T=0.880C=0.120
1000GenomesEuropeSub1006T=0.956C=0.044
1000GenomesGlobalStudy-wide5008T=0.930C=0.070
1000GenomesSouth AsianSub978T=0.940C=0.060
The Genome Aggregation DatabaseAfricanSub8720T=0.928C=0.072
The Genome Aggregation DatabaseAmericanSub838T=0.960C=0.040
The Genome Aggregation DatabaseEast AsianSub1616T=0.867C=0.133
The Genome Aggregation DatabaseEuropeSub18474T=0.945C=0.054
The Genome Aggregation DatabaseGlobalStudy-wide29950T=0.936C=0.064
The Genome Aggregation DatabaseOtherSub302T=0.920C=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.944C=0.055
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs77924860.00013alcohol consumption (maxi-drinks)24277619

eQTL of rs7792486 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7792486 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7103436371103436511E07014259
chr7103438165103438354E07016053
chr7103391868103392296E081-29816