rs7797010

Homo sapiens
G>T
LOC100505938 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0087 (2624/29958,GnomAD)
T=0109 (3199/29118,TOPMED)
T=0128 (639/5008,1000G)
T=0076 (292/3854,ALSPAC)
T=0072 (267/3708,TWINSUK)
chr7:8290132 (GRCh38.p7) (7p21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.8290132G>T
GRCh37.p13 chr 7NC_000007.13:g.8329762G>T

Gene: LOC100505938, uncharacterized LOC100505938(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC100505938 transcriptNR_125740.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.837T=0.163
1000GenomesAmericanSub694G=0.880T=0.120
1000GenomesEast AsianSub1008G=0.900T=0.100
1000GenomesEuropeSub1006G=0.920T=0.080
1000GenomesGlobalStudy-wide5008G=0.872T=0.128
1000GenomesSouth AsianSub978G=0.840T=0.160
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.924T=0.076
The Genome Aggregation DatabaseAfricanSub8720G=0.858T=0.142
The Genome Aggregation DatabaseAmericanSub838G=0.870T=0.130
The Genome Aggregation DatabaseEast AsianSub1620G=0.891T=0.109
The Genome Aggregation DatabaseEuropeSub18478G=0.941T=0.058
The Genome Aggregation DatabaseGlobalStudy-wide29958G=0.912T=0.087
The Genome Aggregation DatabaseOtherSub302G=0.950T=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.890T=0.109
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.928T=0.072
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs77970100.000917alcohol dependence24277619

eQTL of rs7797010 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7797010 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr782939088293978E067-35784
chr782995888299792E073-29970


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr783004018302825E067-26937
chr783004018302825E068-26937
chr783004018302825E069-26937
chr783004018302825E070-26937
chr783004018302825E071-26937
chr783004018302825E072-26937
chr783004018302825E073-26937
chr783004018302825E074-26937
chr783004018302825E082-26937