rs7799136

Homo sapiens
C>T
SVOPL : 3 Prime UTR Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0316 (9474/29902,GnomAD)
T=0350 (10215/29118,TOPMED)
T=0248 (1241/5008,1000G)
T=0349 (1344/3854,ALSPAC)
T=0335 (1241/3708,TWINSUK)
chr7:138591889 (GRCh38.p7) (7q34)
ND
GWASdb2
1   publication(s)
See rs on genome
32 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.138591889C>T
GRCh37.p13 chr 7NC_000007.13:g.138276634C>T

Gene: SVOPL, SVOP like(minus strand)

Molecule type Change Amino acid[Codon] SO Term
SVOPL transcript variant 1NM_001139456.1:c.N/AGenic Downstream Transcript Variant
SVOPL transcript variant 2NM_174959.3:c.N/AGenic Downstream Transcript Variant
SVOPL transcript variant X1XM_005250143.3:c.N/A3 Prime UTR Variant
SVOPL transcript variant X2XM_017011746.1:c.N/A3 Prime UTR Variant
SVOPL transcript variant X4XM_017011747.1:c.N/A3 Prime UTR Variant
SVOPL transcript variant X5XM_011515797.2:c.N/A3 Prime UTR Variant
SVOPL transcript variant X6XM_017011748.1:c.N/A3 Prime UTR Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.551T=0.449
1000GenomesAmericanSub694C=0.750T=0.250
1000GenomesEast AsianSub1008C=0.999T=0.001
1000GenomesEuropeSub1006C=0.655T=0.345
1000GenomesGlobalStudy-wide5008C=0.752T=0.248
1000GenomesSouth AsianSub978C=0.870T=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.651T=0.349
The Genome Aggregation DatabaseAfricanSub8704C=0.570T=0.430
The Genome Aggregation DatabaseAmericanSub836C=0.800T=0.200
The Genome Aggregation DatabaseEast AsianSub1622C=0.999T=0.001
The Genome Aggregation DatabaseEuropeSub18440C=0.705T=0.294
The Genome Aggregation DatabaseGlobalStudy-wide29902C=0.683T=0.316
The Genome Aggregation DatabaseOtherSub300C=0.570T=0.430
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.649T=0.350
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.665T=0.335
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs77991362.43E-05alcohol and nictotine co-dependence20158304

eQTL of rs7799136 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7799136 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7138293522138293633E06816888
chr7138293681138293731E06817047
chr7138292004138292226E07015370
chr7138292256138292347E07015622
chr7138293522138293633E07016888
chr7138293681138293731E07017047
chr7138293906138294186E07017272
chr7138244723138244810E074-31824
chr7138244961138245048E074-31586
chr7138245057138245230E074-31404
chr7138245358138245408E074-31226
chr7138293522138293633E08116888
chr7138293681138293731E08117047
chr7138305585138305635E08128951
chr7138305995138306541E08129361
chr7138307632138307930E08130998
chr7138307974138308024E08131340
chr7138309970138310114E08133336
chr7138310251138310412E08133617
chr7138310413138311040E08133779
chr7138311449138311546E08134815
chr7138311654138312478E08135020
chr7138312630138312670E08135996
chr7138312723138312870E08136089
chr7138313185138313235E08136551
chr7138317464138317627E08140830
chr7138317764138317903E08141130
chr7138317953138317993E08141319
chr7138318048138318140E08141414
chr7138312630138312670E08235996
chr7138312723138312870E08236089
chr7138313185138313235E08236551