rs7804771

Homo sapiens
C>G
DGKI : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0172 (5157/29934,GnomAD)
C==0176 (5136/29118,TOPMED)
C==0190 (950/5008,1000G)
C==0101 (388/3854,ALSPAC)
C==0097 (359/3708,TWINSUK)
chr7:137447847 (GRCh38.p7) (7q33)
ND
GWASdb2
1   publication(s)
See rs on genome
133 Enhancers around
6 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.137447847C>G
GRCh37.p13 chr 7NC_000007.13:g.137132593C>G

Gene: DGKI, diacylglycerol kinase iota(minus strand)

Molecule type Change Amino acid[Codon] SO Term
DGKI transcript variant 2NM_001321708.1:c.N/AIntron Variant
DGKI transcript variant 3NM_001321709.1:c.N/AIntron Variant
DGKI transcript variant 4NM_001321710.1:c.N/AIntron Variant
DGKI transcript variant 1NM_004717.3:c.N/AIntron Variant
DGKI transcript variant X6XM_011516682.2:c.N/AIntron Variant
DGKI transcript variant X11XM_011516684.2:c.N/AIntron Variant
DGKI transcript variant X1XM_017012780.1:c.N/AIntron Variant
DGKI transcript variant X2XM_017012781.1:c.N/AIntron Variant
DGKI transcript variant X3XM_017012782.1:c.N/AIntron Variant
DGKI transcript variant X4XM_017012783.1:c.N/AIntron Variant
DGKI transcript variant X5XM_017012784.1:c.N/AIntron Variant
DGKI transcript variant X7XM_017012785.1:c.N/AIntron Variant
DGKI transcript variant X8XM_017012786.1:c.N/AIntron Variant
DGKI transcript variant X9XM_017012787.1:c.N/AIntron Variant
DGKI transcript variant X10XM_017012788.1:c.N/AIntron Variant
DGKI transcript variant X12XM_017012789.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.281G=0.719
1000GenomesAmericanSub694C=0.160G=0.840
1000GenomesEast AsianSub1008C=0.296G=0.704
1000GenomesEuropeSub1006C=0.102G=0.898
1000GenomesGlobalStudy-wide5008C=0.190G=0.810
1000GenomesSouth AsianSub978C=0.070G=0.930
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.101G=0.899
The Genome Aggregation DatabaseAfricanSub8708C=0.269G=0.731
The Genome Aggregation DatabaseAmericanSub838C=0.160G=0.840
The Genome Aggregation DatabaseEast AsianSub1604C=0.311G=0.689
The Genome Aggregation DatabaseEuropeSub18482C=0.117G=0.883
The Genome Aggregation DatabaseGlobalStudy-wide29934C=0.172G=0.827
The Genome Aggregation DatabaseOtherSub302C=0.060G=0.940
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.176G=0.823
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.097G=0.903
PMID Title Author Journal
18227835Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking.Berrettini WMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs78047719.81E-05nicotine dependence18227835

eQTL of rs7804771 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7804771 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7137086971137087205E067-45388
chr7137094171137094221E067-38372
chr7137103531137103728E067-28865
chr7137103745137103941E067-28652
chr7137104026137104066E067-28527
chr7137105843137106155E067-26438
chr7137106188137106459E067-26134
chr7137106477137106613E067-25980
chr7137106652137106699E067-25894
chr7137106721137106926E067-25667
chr7137119413137119493E067-13100
chr7137119538137120050E067-12543
chr7137120116137120349E067-12244
chr7137124402137124489E067-8104
chr7137124525137125638E067-6955
chr7137137531137137636E0674938
chr7137137691137137787E0675098
chr7137086971137087205E068-45388
chr7137089324137089430E068-43163
chr7137089438137089524E068-43069
chr7137089575137089691E068-42902
chr7137089742137089802E068-42791
chr7137089826137089895E068-42698
chr7137090096137090146E068-42447
chr7137105843137106155E068-26438
chr7137106188137106459E068-26134
chr7137106477137106613E068-25980
chr7137106652137106699E068-25894
chr7137106721137106926E068-25667
chr7137119413137119493E068-13100
chr7137119538137120050E068-12543
chr7137120116137120349E068-12244
chr7137124402137124489E068-8104
chr7137124525137125638E068-6955
chr7137147444137147602E06814851
chr7137147695137147864E06815102
chr7137176920137176970E06844327
chr7137177044137177114E06844451
chr7137177466137177553E06844873
chr7137177592137177683E06844999
chr7137086608137086684E069-45909
chr7137086715137086894E069-45699
chr7137086971137087205E069-45388
chr7137094171137094221E069-38372
chr7137103531137103728E069-28865
chr7137103745137103941E069-28652
chr7137105843137106155E069-26438
chr7137119413137119493E069-13100
chr7137119538137120050E069-12543
chr7137120116137120349E069-12244
chr7137120658137120708E069-11885
chr7137120723137120818E069-11775
chr7137124402137124489E069-8104
chr7137124525137125638E069-6955
chr7137125680137125830E069-6763
chr7137137531137137636E0694938
chr7137137691137137787E0695098
chr7137087319137087991E070-44602
chr7137088010137088145E070-44448
chr7137105843137106155E070-26438
chr7137106188137106459E070-26134
chr7137106477137106613E070-25980
chr7137106652137106699E070-25894
chr7137106721137106926E070-25667
chr7137119413137119493E070-13100
chr7137119538137120050E070-12543
chr7137120116137120349E070-12244
chr7137086608137086684E071-45909
chr7137086715137086894E071-45699
chr7137086971137087205E071-45388
chr7137088873137088945E071-43648
chr7137089324137089430E071-43163
chr7137089438137089524E071-43069
chr7137089575137089691E071-42902
chr7137089742137089802E071-42791
chr7137105843137106155E071-26438
chr7137106188137106459E071-26134
chr7137106477137106613E071-25980
chr7137119413137119493E071-13100
chr7137119538137120050E071-12543
chr7137120658137120708E071-11885
chr7137120723137120818E071-11775
chr7137124402137124489E071-8104
chr7137124525137125638E071-6955
chr7137125680137125830E071-6763
chr7137132267137132548E071-45
chr7137132640137132699E07147
chr7137137531137137636E0714938
chr7137086608137086684E072-45909
chr7137086715137086894E072-45699
chr7137086971137087205E072-45388
chr7137087319137087991E072-44602
chr7137091959137092114E072-40479
chr7137092315137092365E072-40228
chr7137103531137103728E072-28865
chr7137103745137103941E072-28652
chr7137119413137119493E072-13100
chr7137119538137120050E072-12543
chr7137120116137120349E072-12244
chr7137124402137124489E072-8104
chr7137124525137125638E072-6955
chr7137105843137106155E073-26438
chr7137119538137120050E073-12543
chr7137120116137120349E073-12244
chr7137124402137124489E073-8104
chr7137124525137125638E073-6955
chr7137086608137086684E074-45909
chr7137086715137086894E074-45699
chr7137086971137087205E074-45388
chr7137091719137091803E074-40790
chr7137105843137106155E074-26438
chr7137106188137106459E074-26134
chr7137106477137106613E074-25980
chr7137119413137119493E074-13100
chr7137119538137120050E074-12543
chr7137120116137120349E074-12244
chr7137120658137120708E074-11885
chr7137120723137120818E074-11775
chr7137124402137124489E074-8104
chr7137124525137125638E074-6955
chr7137125680137125830E074-6763
chr7137137691137137787E0745098
chr7137087319137087991E081-44602
chr7137088010137088145E081-44448
chr7137088194137088410E081-44183
chr7137152676137152736E08120083
chr7137086608137086684E082-45909
chr7137086715137086894E082-45699
chr7137086971137087205E082-45388
chr7137087319137087991E082-44602
chr7137088010137088145E082-44448
chr7137088194137088410E082-44183
chr7137099615137099946E082-32647










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr7137137819137138511E0675226
chr7137137819137138511E0685226
chr7137137819137138511E0695226
chr7137137819137138511E0715226
chr7137137819137138511E0725226
chr7137137819137138511E0735226