rs7805181

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0209 (6258/29922,GnomAD)
T==0193 (5621/29118,TOPMED)
T==0262 (1312/5008,1000G)
T==0187 (721/3854,ALSPAC)
T==0182 (674/3708,TWINSUK)
chr7:3050648 (GRCh38.p7) (7p22.2)
AD
GWASdb2
1   publication(s)
See rs on genome
13 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.3050648T>C
GRCh37.p13 chr 7NC_000007.13:g.3090282T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.184C=0.816
1000GenomesAmericanSub694T=0.230C=0.770
1000GenomesEast AsianSub1008T=0.374C=0.626
1000GenomesEuropeSub1006T=0.177C=0.823
1000GenomesGlobalStudy-wide5008T=0.262C=0.738
1000GenomesSouth AsianSub978T=0.360C=0.640
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.187C=0.813
The Genome Aggregation DatabaseAfricanSub8710T=0.193C=0.807
The Genome Aggregation DatabaseAmericanSub834T=0.200C=0.800
The Genome Aggregation DatabaseEast AsianSub1610T=0.372C=0.628
The Genome Aggregation DatabaseEuropeSub18466T=0.204C=0.795
The Genome Aggregation DatabaseGlobalStudy-wide29922T=0.209C=0.790
The Genome Aggregation DatabaseOtherSub302T=0.130C=0.870
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.193C=0.807
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.182C=0.818
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs78051810.00093alcohol dependence20201924

eQTL of rs7805181 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7805181 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr730676533068113E070-22169
chr730682373068513E070-21769
chr730781153078261E070-12021
chr730783213078439E070-11843
chr730785143078598E070-11684
chr730666633066946E081-23336
chr730670093067401E081-22881
chr730682373068513E081-21769
chr730686123068761E081-21521
chr730689423069047E081-21235
chr730935313093598E0813249
chr731230463123217E08132764
chr731237463123816E08133464