rs7824584

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0446 (13367/29944,GnomAD)
T==0391 (11395/29118,TOPMED)
T==0365 (1827/5008,1000G)
T==0468 (1804/3854,ALSPAC)
T==0452 (1676/3708,TWINSUK)
chr8:120958799 (GRCh38.p7) (8q24.12)
AD
GWASdb2
1   publication(s)
See rs on genome
36 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.120958799T>C
GRCh37.p13 chr 8NC_000008.10:g.121971039T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.374C=0.626
1000GenomesAmericanSub694T=0.370C=0.630
1000GenomesEast AsianSub1008T=0.325C=0.675
1000GenomesEuropeSub1006T=0.456C=0.544
1000GenomesGlobalStudy-wide5008T=0.365C=0.635
1000GenomesSouth AsianSub978T=0.290C=0.710
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.468C=0.532
The Genome Aggregation DatabaseAfricanSub8714T=0.379C=0.621
The Genome Aggregation DatabaseAmericanSub836T=0.360C=0.640
The Genome Aggregation DatabaseEast AsianSub1620T=0.312C=0.688
The Genome Aggregation DatabaseEuropeSub18472T=0.494C=0.505
The Genome Aggregation DatabaseGlobalStudy-wide29944T=0.446C=0.553
The Genome Aggregation DatabaseOtherSub302T=0.450C=0.550
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.391C=0.608
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.452C=0.548
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs78245840.00074alcohol dependence20201924

eQTL of rs7824584 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7824584 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8121945002121945454E068-25585
chr8121945502121945872E068-25167
chr8121945920121946003E068-25036
chr8121946044121946162E068-24877
chr8121946193121946251E068-24788
chr8121945502121945872E069-25167
chr8121945920121946003E069-25036
chr8121972229121973105E0701190
chr8121945002121945454E071-25585
chr8121945502121945872E071-25167
chr8121945920121946003E071-25036
chr8121946044121946162E071-24877
chr8121946193121946251E071-24788
chr8121945002121945454E072-25585
chr8121945502121945872E072-25167
chr8121945920121946003E072-25036
chr8121946044121946162E072-24877
chr8121946193121946251E072-24788
chr8121945002121945454E073-25585
chr8121945502121945872E073-25167
chr8121945920121946003E073-25036
chr8121945002121945454E074-25585
chr8121945502121945872E074-25167
chr8121945920121946003E074-25036
chr8121965369121965461E081-5578
chr8121965509121965563E081-5476
chr8121965682121965737E081-5302
chr8121965937121966187E081-4852
chr8121967350121967436E081-3603
chr8121967861121968080E081-2959
chr8122001050122001802E08130011
chr8122001814122002166E08130775
chr8121949997121950051E082-20988
chr8121950076121950624E082-20415
chr8121971849121972024E082810
chr8121972229121973105E0821190