rs7833568

Homo sapiens
T>A / T>C
CNBD1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0276 (8277/29914,GnomAD)
T==0263 (7667/29118,TOPMED)
T==0386 (1933/5008,1000G)
T==0282 (1087/3854,ALSPAC)
T==0278 (1029/3708,TWINSUK)
chr8:87249563 (GRCh38.p7) (8q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.87249563T>A
GRCh38.p7 chr 8NC_000008.11:g.87249563T>C
GRCh37.p13 chr 8NC_000008.10:g.88261791T>A
GRCh37.p13 chr 8NC_000008.10:g.88261791T>C

Gene: CNBD1, cyclic nucleotide binding domain containing 1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
CNBD1 transcriptNM_173538.2:c.N/AIntron Variant
CNBD1 transcript variant X2XM_017013149.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.212C=0.788
1000GenomesAmericanSub694T=0.430C=0.570
1000GenomesEast AsianSub1008T=0.598C=0.402
1000GenomesEuropeSub1006T=0.300C=0.700
1000GenomesGlobalStudy-wide5008T=0.386C=0.614
1000GenomesSouth AsianSub978T=0.460C=0.540
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.282C=0.718
The Genome Aggregation DatabaseAfricanSub8702T=0.207C=0.793
The Genome Aggregation DatabaseAmericanSub832T=0.450C=0.550
The Genome Aggregation DatabaseEast AsianSub1600T=0.641C=0.359
The Genome Aggregation DatabaseEuropeSub18478T=0.270C=0.729
The Genome Aggregation DatabaseGlobalStudy-wide29914T=0.276C=0.723
The Genome Aggregation DatabaseOtherSub302T=0.270C=0.730
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.263C=0.736
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.278C=0.722
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs78335680.0000355alcoholismpha002891
rs78335680.0000355alcohol dependence20201924

eQTL of rs7833568 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7833568 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.