rs7834483

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0287 (8565/29824,GnomAD)
A==0272 (7926/29118,TOPMED)
A==0327 (1638/5008,1000G)
A==0336 (1294/3854,ALSPAC)
A==0330 (1223/3708,TWINSUK)
chr8:81792593 (GRCh38.p7) (8q21.13)
AD
GWASdb2
1   publication(s)
See rs on genome
93 Enhancers around
34 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.81792593A>G
GRCh37.p13 chr 8NC_000008.10:g.82704828A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.142G=0.858
1000GenomesAmericanSub694A=0.350G=0.650
1000GenomesEast AsianSub1008A=0.551G=0.449
1000GenomesEuropeSub1006A=0.338G=0.662
1000GenomesGlobalStudy-wide5008A=0.327G=0.673
1000GenomesSouth AsianSub978A=0.320G=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.336G=0.664
The Genome Aggregation DatabaseAfricanSub8692A=0.166G=0.834
The Genome Aggregation DatabaseAmericanSub822A=0.320G=0.680
The Genome Aggregation DatabaseEast AsianSub1612A=0.582G=0.418
The Genome Aggregation DatabaseEuropeSub18398A=0.315G=0.684
The Genome Aggregation DatabaseGlobalStudy-wide29824A=0.287G=0.712
The Genome Aggregation DatabaseOtherSub300A=0.380G=0.620
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.272G=0.727
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.330G=0.670
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs78344835.65E-05alcohol consumption23743675

eQTL of rs7834483 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7834483 in Fetal Brain

Probe ID Position Gene beta p-value
cg17211192chr8:82754475SNX160.06129432350328671.2172e-22
cg23324259chr8:82754387SNX160.0185826667542042.5414e-15
cg27398817chr8:82754497SNX160.03761430564339682.5760e-14

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr88272692182727044E06722093
chr88272708482727145E06722256
chr88272739782727713E06722569
chr88275141582751459E06746587
chr88275155182751632E06746723
chr88275169382751743E06746865
chr88275176982751905E06746941
chr88275192082751978E06747092
chr88275205182752101E06747223
chr88275213682752286E06747308
chr88275242482752500E06747596
chr88275252382752586E06747695
chr88274913582749745E06844307
chr88275040382750493E06845575
chr88275055782750622E06845729
chr88275073382750913E06845905
chr88275118682751259E06846358
chr88275141582751459E06846587
chr88275155182751632E06846723
chr88275169382751743E06846865
chr88275242482752500E06847596
chr88275252382752586E06847695
chr88275264882752702E06847820
chr88275205182752101E06947223
chr88275213682752286E06947308
chr88275242482752500E06947596
chr88275252382752586E06947695
chr88275264882752702E06947820
chr88270876682709232E0703938
chr88270927582709325E0704447
chr88270935482709440E0704526
chr88273635982736422E07031531
chr88273760682737656E07032778
chr88273770482737783E07032876
chr88274913582749745E07044307
chr88272692182727044E07122093
chr88272739782727713E07122569
chr88275040382750493E07145575
chr88275055782750622E07145729
chr88275073382750913E07145905
chr88275176982751905E07146941
chr88275192082751978E07147092
chr88275205182752101E07147223
chr88275213682752286E07147308
chr88275242482752500E07147596
chr88275252382752586E07147695
chr88275264882752702E07147820
chr88269268482693377E072-11451
chr88272629482726439E07221466
chr88272692182727044E07222093
chr88272708482727145E07222256
chr88272739782727713E07222569
chr88272739782727713E07322569
chr88272692182727044E07422093
chr88275040382750493E07445575
chr88275055782750622E07445729
chr88275073382750913E07445905
chr88275118682751259E07446358
chr88275141582751459E07446587
chr88275155182751632E07446723
chr88275169382751743E07446865
chr88275176982751905E07446941
chr88275192082751978E07447092
chr88275205182752101E07447223
chr88275213682752286E07447308
chr88275242482752500E07447596
chr88275252382752586E07447695
chr88275264882752702E07447820
chr88269268482693377E081-11451
chr88274894182748991E08144113
chr88275118682751259E08146358
chr88275141582751459E08146587
chr88275155182751632E08146723
chr88275169382751743E08146865
chr88275176982751905E08146941
chr88275192082751978E08147092
chr88275205182752101E08147223
chr88275213682752286E08147308
chr88275242482752500E08147596
chr88275252382752586E08147695
chr88275264882752702E08147820
chr88269939382699447E082-5381
chr88269957982699654E082-5174
chr88274913582749745E08244307
chr88274982582749873E08244997
chr88275155182751632E08246723
chr88275169382751743E08246865
chr88275176982751905E08246941
chr88275192082751978E08247092
chr88275205182752101E08247223
chr88275213682752286E08247308
chr88275242482752500E08247596
chr88275252382752586E08247695










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr88275290282753069E06748074
chr88275314082753307E06748312
chr88275349982753591E06748671
chr88275360282754599E06748774
chr88275349982753591E06848671
chr88275360282754599E06848774
chr88275290282753069E06948074
chr88275314082753307E06948312
chr88275349982753591E06948671
chr88275360282754599E06948774
chr88275290282753069E07048074
chr88275314082753307E07048312
chr88275349982753591E07048671
chr88275360282754599E07048774
chr88275290282753069E07148074
chr88275314082753307E07148312
chr88275349982753591E07148671
chr88275360282754599E07148774
chr88275290282753069E07248074
chr88275314082753307E07248312
chr88275349982753591E07248671
chr88275360282754599E07248774
chr88275290282753069E07348074
chr88275314082753307E07348312
chr88275349982753591E07348671
chr88275360282754599E07348774
chr88275314082753307E07448312
chr88275349982753591E07448671
chr88275360282754599E07448774
chr88275360282754599E08148774
chr88275290282753069E08248074
chr88275314082753307E08248312
chr88275349982753591E08248671
chr88275360282754599E08248774