rs7834555

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0290 (8702/29912,GnomAD)
A==0276 (8037/29118,TOPMED)
A==0328 (1644/5008,1000G)
A==0339 (1306/3854,ALSPAC)
A==0332 (1231/3708,TWINSUK)
chr8:81785390 (GRCh38.p7) (8q21.13)
AD
GWASdb2
1   publication(s)
See rs on genome
21 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.81785390A>G
GRCh37.p13 chr 8NC_000008.10:g.82697625A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.142G=0.858
1000GenomesAmericanSub694A=0.350G=0.650
1000GenomesEast AsianSub1008A=0.554G=0.446
1000GenomesEuropeSub1006A=0.340G=0.660
1000GenomesGlobalStudy-wide5008A=0.328G=0.672
1000GenomesSouth AsianSub978A=0.320G=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.339G=0.661
The Genome Aggregation DatabaseAfricanSub8710A=0.167G=0.833
The Genome Aggregation DatabaseAmericanSub836A=0.320G=0.680
The Genome Aggregation DatabaseEast AsianSub1608A=0.580G=0.420
The Genome Aggregation DatabaseEuropeSub18458A=0.321G=0.678
The Genome Aggregation DatabaseGlobalStudy-wide29912A=0.290G=0.709
The Genome Aggregation DatabaseOtherSub300A=0.380G=0.620
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.276G=0.724
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.332G=0.668
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs78345553.43E-05alcohol consumption23743675

eQTL of rs7834555 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7834555 in Fetal Brain

Probe ID Position Gene beta p-value
cg17211192chr8:82754475SNX160.06175045250404923.4143e-23
cg23324259chr8:82754387SNX160.01876774609066619.8973e-16
cg27398817chr8:82754497SNX160.03799498698989571.0755e-14

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr88272692182727044E06729296
chr88272708482727145E06729459
chr88272739782727713E06729772
chr88270876682709232E07011141
chr88270927582709325E07011650
chr88270935482709440E07011729
chr88273635982736422E07038734
chr88273760682737656E07039981
chr88273770482737783E07040079
chr88272692182727044E07129296
chr88272739782727713E07129772
chr88269268482693377E072-4248
chr88272629482726439E07228669
chr88272692182727044E07229296
chr88272708482727145E07229459
chr88272739782727713E07229772
chr88272739782727713E07329772
chr88272692182727044E07429296
chr88269268482693377E081-4248
chr88269939382699447E0821768
chr88269957982699654E0821954