rs7835342

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0291 (8716/29952,GnomAD)
A==0276 (8046/29118,TOPMED)
A==0329 (1646/5008,1000G)
A==0339 (1307/3854,ALSPAC)
A==0332 (1231/3708,TWINSUK)
chr8:81785857 (GRCh38.p7) (8q21.13)
AD
GWASdb2
1   publication(s)
See rs on genome
21 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.81785857A>G
GRCh37.p13 chr 8NC_000008.10:g.82698092A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.142G=0.858
1000GenomesAmericanSub694A=0.350G=0.650
1000GenomesEast AsianSub1008A=0.554G=0.446
1000GenomesEuropeSub1006A=0.341G=0.659
1000GenomesGlobalStudy-wide5008A=0.329G=0.671
1000GenomesSouth AsianSub978A=0.320G=0.680
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.339G=0.661
The Genome Aggregation DatabaseAfricanSub8716A=0.167G=0.833
The Genome Aggregation DatabaseAmericanSub836A=0.320G=0.680
The Genome Aggregation DatabaseEast AsianSub1612A=0.578G=0.422
The Genome Aggregation DatabaseEuropeSub18486A=0.321G=0.678
The Genome Aggregation DatabaseGlobalStudy-wide29952A=0.291G=0.709
The Genome Aggregation DatabaseOtherSub302A=0.380G=0.620
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.276G=0.723
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.332G=0.668
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs78353423.08E-05alcohol consumption23743675

eQTL of rs7835342 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7835342 in Fetal Brain

Probe ID Position Gene beta p-value
cg17211192chr8:82754475SNX160.06175045250404923.4143e-23
cg23324259chr8:82754387SNX160.01876774609066619.8973e-16
cg27398817chr8:82754497SNX160.03799498698989571.0755e-14

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr88272692182727044E06728829
chr88272708482727145E06728992
chr88272739782727713E06729305
chr88270876682709232E07010674
chr88270927582709325E07011183
chr88270935482709440E07011262
chr88273635982736422E07038267
chr88273760682737656E07039514
chr88273770482737783E07039612
chr88272692182727044E07128829
chr88272739782727713E07129305
chr88269268482693377E072-4715
chr88272629482726439E07228202
chr88272692182727044E07228829
chr88272708482727145E07228992
chr88272739782727713E07229305
chr88272739782727713E07329305
chr88272692182727044E07428829
chr88269268482693377E081-4715
chr88269939382699447E0821301
chr88269957982699654E0821487