rs7835613

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0228 (6822/29832,GnomAD)
A=0246 (7190/29118,TOPMED)
A=0235 (1175/5008,1000G)
A=0228 (880/3854,ALSPAC)
A=0233 (865/3708,TWINSUK)
chr8:142601067 (GRCh38.p7) (8q24.3)
ND
GWASdb2
1   publication(s)
See rs on genome
359 Enhancers around
6 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.142601067G>A
GRCh37.p13 chr 8NC_000008.10:g.143682428G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.789A=0.211
1000GenomesAmericanSub694G=0.800A=0.200
1000GenomesEast AsianSub1008G=0.813A=0.187
1000GenomesEuropeSub1006G=0.718A=0.282
1000GenomesGlobalStudy-wide5008G=0.765A=0.235
1000GenomesSouth AsianSub978G=0.710A=0.290
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.772A=0.228
The Genome Aggregation DatabaseAfricanSub8672G=0.787A=0.213
The Genome Aggregation DatabaseAmericanSub836G=0.800A=0.200
The Genome Aggregation DatabaseEast AsianSub1620G=0.834A=0.166
The Genome Aggregation DatabaseEuropeSub18402G=0.759A=0.240
The Genome Aggregation DatabaseGlobalStudy-wide29832G=0.771A=0.228
The Genome Aggregation DatabaseOtherSub302G=0.630A=0.370
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.753A=0.246
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.767A=0.233
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs78356130.000921nicotine dependence17158188

eQTL of rs7835613 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7835613 in Fetal Brain

Probe ID Position Gene beta p-value
cg01509843chr8:143695822ARC0.007037753209167821.6093e-15

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8143647990143648114E067-34314
chr8143648139143648205E067-34223
chr8143648222143648287E067-34141
chr8143648385143648812E067-33616
chr8143666403143666532E067-15896
chr8143666546143666596E067-15832
chr8143666621143666687E067-15741
chr8143678709143678781E067-3647
chr8143678825143679473E067-2955
chr8143679685143679745E067-2683
chr8143679826143680140E067-2288
chr8143680229143680279E067-2149
chr8143680324143680514E067-1914
chr8143680581143681162E067-1266
chr8143682645143682878E067217
chr8143682935143683294E067507
chr8143683310143683393E067882
chr8143689963143690023E0677535
chr8143690135143690191E0677707
chr8143690257143691125E0677829
chr8143702411143702461E06719983
chr8143702537143702625E06720109
chr8143702782143702832E06720354
chr8143703298143703818E06720870
chr8143703848143703982E06721420
chr8143704057143704409E06721629
chr8143704470143704524E06722042
chr8143704588143704659E06722160
chr8143704758143704849E06722330
chr8143704882143704922E06722454
chr8143708745143708824E06726317
chr8143708851143708905E06726423
chr8143709043143709097E06726615
chr8143709236143709322E06726808
chr8143709561143709790E06727133
chr8143680581143681162E068-1266
chr8143689963143690023E0687535
chr8143690135143690191E0687707
chr8143690257143691125E0687829
chr8143692853143693354E06810425
chr8143693379143693642E06810951
chr8143693709143693763E06811281
chr8143697230143697287E06814802
chr8143697355143697418E06814927
chr8143697593143697646E06815165
chr8143697678143697821E06815250
chr8143697874143697947E06815446
chr8143698014143698306E06815586
chr8143703298143703818E06820870
chr8143703848143703982E06821420
chr8143704057143704409E06821629
chr8143704470143704524E06822042
chr8143704588143704659E06822160
chr8143704758143704849E06822330
chr8143704882143704922E06822454
chr8143705130143705880E06822702
chr8143714655143714797E06832227
chr8143714807143714876E06832379
chr8143714924143715007E06832496
chr8143715227143715359E06832799
chr8143647990143648114E069-34314
chr8143648139143648205E069-34223
chr8143648222143648287E069-34141
chr8143648385143648812E069-33616
chr8143678825143679473E069-2955
chr8143689963143690023E0697535
chr8143690135143690191E0697707
chr8143690257143691125E0697829
chr8143693379143693642E06910951
chr8143693709143693763E06911281
chr8143697230143697287E06914802
chr8143697355143697418E06914927
chr8143697593143697646E06915165
chr8143697678143697821E06915250
chr8143697874143697947E06915446
chr8143698014143698306E06915586
chr8143702782143702832E06920354
chr8143702992143703042E06920564
chr8143703043143703120E06920615
chr8143703298143703818E06920870
chr8143703848143703982E06921420
chr8143704057143704409E06921629
chr8143704470143704524E06922042
chr8143704588143704659E06922160
chr8143704758143704849E06922330
chr8143704882143704922E06922454
chr8143705130143705880E06922702
chr8143709043143709097E06926615
chr8143709236143709322E06926808
chr8143709561143709790E06927133
chr8143712938143713091E06930510
chr8143713219143713269E06930791
chr8143648139143648205E070-34223
chr8143648222143648287E070-34141
chr8143648385143648812E070-33616
chr8143656367143656516E070-25912
chr8143656603143656704E070-25724
chr8143657042143657092E070-25336
chr8143669482143669611E070-12817
chr8143669766143669832E070-12596
chr8143669962143670021E070-12407
chr8143678825143679473E070-2955
chr8143679685143679745E070-2683
chr8143679826143680140E070-2288
chr8143680229143680279E070-2149
chr8143680324143680514E070-1914
chr8143680581143681162E070-1266
chr8143681223143681603E070-825
chr8143681612143681662E070-766
chr8143681723143681827E070-601
chr8143681945143681995E070-433
chr8143682110143682154E070-274
chr8143682159143682275E070-153
chr8143682645143682878E070217
chr8143682935143683294E070507
chr8143683310143683393E070882
chr8143683649143683875E0701221
chr8143684295143684396E0701867
chr8143684430143684552E0702002
chr8143689570143689679E0707142
chr8143689724143689947E0707296
chr8143689963143690023E0707535
chr8143690135143690191E0707707
chr8143690257143691125E0707829
chr8143697230143697287E07014802
chr8143697355143697418E07014927
chr8143697593143697646E07015165
chr8143697678143697821E07015250
chr8143697874143697947E07015446
chr8143698014143698306E07015586
chr8143698317143698505E07015889
chr8143698506143698621E07016078
chr8143698828143698905E07016400
chr8143698980143699205E07016552
chr8143699228143699312E07016800
chr8143702782143702832E07020354
chr8143702992143703042E07020564
chr8143703043143703120E07020615
chr8143703298143703818E07020870
chr8143703848143703982E07021420
chr8143704057143704409E07021629
chr8143704470143704524E07022042
chr8143704588143704659E07022160
chr8143704758143704849E07022330
chr8143704882143704922E07022454
chr8143705130143705880E07022702
chr8143715598143715648E07033170
chr8143690257143691125E0717829
chr8143692853143693354E07110425
chr8143697230143697287E07114802
chr8143697355143697418E07114927
chr8143697593143697646E07115165
chr8143697678143697821E07115250
chr8143702992143703042E07120564
chr8143703043143703120E07120615
chr8143703298143703818E07120870
chr8143704057143704409E07121629
chr8143704470143704524E07122042
chr8143704588143704659E07122160
chr8143704758143704849E07122330
chr8143704882143704922E07122454
chr8143705130143705880E07122702
chr8143708745143708824E07126317
chr8143708851143708905E07126423
chr8143709043143709097E07126615
chr8143709236143709322E07126808
chr8143709561143709790E07127133
chr8143712938143713091E07130510
chr8143713219143713269E07130791
chr8143713320143713825E07130892
chr8143714022143714351E07131594
chr8143716039143716453E07133611
chr8143678825143679473E072-2955
chr8143680581143681162E072-1266
chr8143682935143683294E072507
chr8143683310143683393E072882
chr8143683649143683875E0721221
chr8143689963143690023E0727535
chr8143690135143690191E0727707
chr8143690257143691125E0727829
chr8143692853143693354E07210425
chr8143697230143697287E07214802
chr8143697355143697418E07214927
chr8143697593143697646E07215165
chr8143697678143697821E07215250
chr8143697874143697947E07215446
chr8143698014143698306E07215586
chr8143703298143703818E07220870
chr8143703848143703982E07221420
chr8143704057143704409E07221629
chr8143704470143704524E07222042
chr8143704588143704659E07222160
chr8143704758143704849E07222330
chr8143704882143704922E07222454
chr8143705130143705880E07222702
chr8143708745143708824E07226317
chr8143708851143708905E07226423
chr8143709043143709097E07226615
chr8143709236143709322E07226808
chr8143709561143709790E07227133
chr8143713219143713269E07230791
chr8143714807143714876E07232379
chr8143714924143715007E07232496
chr8143716039143716453E07233611
chr8143718025143718075E07235597
chr8143718179143718659E07235751
chr8143648385143648812E073-33616
chr8143661620143661670E073-20758
chr8143678825143679473E073-2955
chr8143679685143679745E073-2683
chr8143679826143680140E073-2288
chr8143680229143680279E073-2149
chr8143680324143680514E073-1914
chr8143680581143681162E073-1266
chr8143681223143681603E073-825
chr8143682935143683294E073507
chr8143683310143683393E073882
chr8143689140143689402E0736712
chr8143689570143689679E0737142
chr8143689724143689947E0737296
chr8143689963143690023E0737535
chr8143690135143690191E0737707
chr8143690257143691125E0737829
chr8143692853143693354E07310425
chr8143697230143697287E07314802
chr8143697355143697418E07314927
chr8143697593143697646E07315165
chr8143697678143697821E07315250
chr8143697874143697947E07315446
chr8143698014143698306E07315586
chr8143702537143702625E07320109
chr8143702782143702832E07320354
chr8143702992143703042E07320564
chr8143703043143703120E07320615
chr8143703298143703818E07320870
chr8143703848143703982E07321420
chr8143704057143704409E07321629
chr8143704470143704524E07322042
chr8143704588143704659E07322160
chr8143704758143704849E07322330
chr8143704882143704922E07322454
chr8143705130143705880E07322702
chr8143716039143716453E07333611
chr8143703298143703818E07420870
chr8143703848143703982E07421420
chr8143704057143704409E07421629
chr8143704470143704524E07422042
chr8143704588143704659E07422160
chr8143704758143704849E07422330
chr8143704882143704922E07422454
chr8143705130143705880E07422702
chr8143712938143713091E07430510
chr8143648385143648812E081-33616
chr8143659778143659911E081-22517
chr8143660117143660432E081-21996
chr8143661620143661670E081-20758
chr8143661721143661864E081-20564
chr8143661868143662242E081-20186
chr8143662335143662743E081-19685
chr8143675405143675494E081-6934
chr8143675604143675664E081-6764
chr8143675798143675908E081-6520
chr8143675937143675987E081-6441
chr8143678709143678781E081-3647
chr8143678825143679473E081-2955
chr8143679685143679745E081-2683
chr8143679826143680140E081-2288
chr8143680229143680279E081-2149
chr8143680324143680514E081-1914
chr8143680581143681162E081-1266
chr8143681223143681603E081-825
chr8143681612143681662E081-766
chr8143681723143681827E081-601
chr8143681945143681995E081-433
chr8143682110143682154E081-274
chr8143682159143682275E081-153
chr8143682645143682878E081217
chr8143682935143683294E081507
chr8143683310143683393E081882
chr8143683649143683875E0811221
chr8143684295143684396E0811867
chr8143689963143690023E0817535
chr8143690135143690191E0817707
chr8143690257143691125E0817829
chr8143693379143693642E08110951
chr8143693709143693763E08111281
chr8143697230143697287E08114802
chr8143697355143697418E08114927
chr8143697593143697646E08115165
chr8143697678143697821E08115250
chr8143697874143697947E08115446
chr8143698014143698306E08115586
chr8143698317143698505E08115889
chr8143698506143698621E08116078
chr8143698980143699205E08116552
chr8143699228143699312E08116800
chr8143702411143702461E08119983
chr8143702537143702625E08120109
chr8143702782143702832E08120354
chr8143702992143703042E08120564
chr8143703043143703120E08120615
chr8143703298143703818E08120870
chr8143703848143703982E08121420
chr8143704057143704409E08121629
chr8143704470143704524E08122042
chr8143704588143704659E08122160
chr8143704758143704849E08122330
chr8143704882143704922E08122454
chr8143705130143705880E08122702
chr8143659403143659463E082-22965
chr8143659528143659578E082-22850
chr8143659778143659911E082-22517
chr8143660117143660432E082-21996
chr8143660555143660669E082-21759
chr8143661620143661670E082-20758
chr8143661721143661864E082-20564
chr8143661868143662242E082-20186
chr8143675038143675141E082-7287
chr8143675250143675389E082-7039
chr8143675405143675494E082-6934
chr8143675604143675664E082-6764
chr8143675798143675908E082-6520
chr8143678825143679473E082-2955
chr8143679685143679745E082-2683
chr8143679826143680140E082-2288
chr8143680229143680279E082-2149
chr8143680324143680514E082-1914
chr8143680581143681162E082-1266
chr8143681223143681603E082-825
chr8143681612143681662E082-766
chr8143681723143681827E082-601
chr8143681945143681995E082-433
chr8143682110143682154E082-274
chr8143682159143682275E082-153
chr8143682645143682878E082217
chr8143682935143683294E082507
chr8143683310143683393E082882
chr8143683649143683875E0821221
chr8143689570143689679E0827142
chr8143689724143689947E0827296
chr8143689963143690023E0827535
chr8143690135143690191E0827707
chr8143690257143691125E0827829
chr8143697230143697287E08214802
chr8143697355143697418E08214927
chr8143697593143697646E08215165
chr8143697678143697821E08215250
chr8143697874143697947E08215446
chr8143698014143698306E08215586
chr8143698980143699205E08216552
chr8143699228143699312E08216800
chr8143699476143699602E08217048
chr8143702537143702625E08220109
chr8143702782143702832E08220354
chr8143702992143703042E08220564
chr8143703043143703120E08220615
chr8143703298143703818E08220870
chr8143703848143703982E08221420
chr8143704057143704409E08221629










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr8143694979143695720E06712551
chr8143694979143695720E06812551
chr8143694979143695720E06912551
chr8143694979143695720E07012551
chr8143694979143695720E07312551
chr8143694979143695720E08212551