rs7835993

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0482 (14430/29906,GnomAD)
G==0499 (14536/29118,TOPMED)
G==0416 (2081/5008,1000G)
A=0324 (1250/3854,ALSPAC)
A=0324 (1200/3708,TWINSUK)
chr8:59308573 (GRCh38.p7) (8q12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
49 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.59308573G>A
GRCh37.p13 chr 8NC_000008.10:g.60221132G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.259A=0.741
1000GenomesAmericanSub694G=0.400A=0.600
1000GenomesEast AsianSub1008G=0.222A=0.778
1000GenomesEuropeSub1006G=0.666A=0.334
1000GenomesGlobalStudy-wide5008G=0.416A=0.584
1000GenomesSouth AsianSub978G=0.580A=0.420
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.676A=0.324
The Genome Aggregation DatabaseAfricanSub8714G=0.311A=0.689
The Genome Aggregation DatabaseAmericanSub832G=0.420A=0.580
The Genome Aggregation DatabaseEast AsianSub1600G=0.221A=0.779
The Genome Aggregation DatabaseEuropeSub18458G=0.642A=0.357
The Genome Aggregation DatabaseGlobalStudy-wide29906G=0.517A=0.482
The Genome Aggregation DatabaseOtherSub302G=0.680A=0.320
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.499A=0.500
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.676A=0.324
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs78359930.000797alcohol dependence20201924

eQTL of rs7835993 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7835993 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr86021845560218555E070-2577
chr86021860160218688E070-2444
chr86022255460222634E0701422
chr86022266860222711E0701536
chr86017752860177642E081-43490
chr86019471960194848E081-26284
chr86019690260197019E081-24113
chr86019712960197231E081-23901
chr86019750060197883E081-23249
chr86020216260202586E081-18546
chr86020264060202734E081-18398
chr86020293360202983E081-18149
chr86020325160203301E081-17831
chr86020396360204309E081-16823
chr86021322260213821E081-7311
chr86021384460214066E081-7066
chr86021742160217543E081-3589
chr86021766360217964E081-3168
chr86021797160218418E081-2714
chr86021845560218555E081-2577
chr86021860160218688E081-2444
chr86021897660220190E081-942
chr86022022960220412E081-720
chr86022072760220781E081-351
chr86022120360222071E08171
chr86022209460222144E081962
chr86022246360222529E0811331
chr86022255460222634E0811422
chr86022266860222711E0811536
chr86022309560223296E0811963
chr86022377560223815E0812643
chr86022409260224142E0812960
chr86022471660224897E0813584
chr86019471960194848E082-26284
chr86019690260197019E082-24113
chr86019712960197231E082-23901
chr86020264060202734E082-18398
chr86020293360202983E082-18149
chr86020325160203301E082-17831
chr86021797160218418E082-2714
chr86021845560218555E082-2577
chr86021860160218688E082-2444
chr86022072760220781E082-351
chr86022120360222071E08271
chr86022209460222144E082962
chr86022246360222529E0821331
chr86022255460222634E0821422
chr86022266860222711E0821536
chr86022309560223296E0821963