rs7839178

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0333 (9985/29954,GnomAD)
G=0343 (10013/29118,TOPMED)
G=0386 (1933/5008,1000G)
G=0332 (1278/3854,ALSPAC)
G=0319 (1184/3708,TWINSUK)
chr8:81851244 (GRCh38.p7) (8q21.13)
AD
GWASdb2
1   publication(s)
See rs on genome
89 Enhancers around
39 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.81851244A>G
GRCh37.p13 chr 8NC_000008.10:g.82763479A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.664G=0.336
1000GenomesAmericanSub694A=0.610G=0.390
1000GenomesEast AsianSub1008A=0.403G=0.597
1000GenomesEuropeSub1006A=0.670G=0.330
1000GenomesGlobalStudy-wide5008A=0.614G=0.386
1000GenomesSouth AsianSub978A=0.710G=0.290
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.668G=0.332
The Genome Aggregation DatabaseAfricanSub8706A=0.666G=0.334
The Genome Aggregation DatabaseAmericanSub836A=0.680G=0.320
The Genome Aggregation DatabaseEast AsianSub1618A=0.370G=0.630
The Genome Aggregation DatabaseEuropeSub18492A=0.692G=0.307
The Genome Aggregation DatabaseGlobalStudy-wide29954A=0.666G=0.333
The Genome Aggregation DatabaseOtherSub302A=0.640G=0.360
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.656G=0.343
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.681G=0.319
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs78391783.51E-05alcohol consumption23743675

eQTL of rs7839178 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7839178 in Fetal Brain

Probe ID Position Gene beta p-value
cg17211192chr8:82754475SNX160.06514329975886591.7902e-27
cg27398817chr8:82754497SNX160.03860539417403211.4948e-15
cg23324259chr8:82754387SNX160.01760124910621795.6813e-14

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr88272692182727044E067-36435
chr88272708482727145E067-36334
chr88272739782727713E067-35766
chr88275141582751459E067-12020
chr88275155182751632E067-11847
chr88275169382751743E067-11736
chr88275176982751905E067-11574
chr88275192082751978E067-11501
chr88275205182752101E067-11378
chr88275213682752286E067-11193
chr88275242482752500E067-10979
chr88275252382752586E067-10893
chr88274913582749745E068-13734
chr88275040382750493E068-12986
chr88275055782750622E068-12857
chr88275073382750913E068-12566
chr88275118682751259E068-12220
chr88275141582751459E068-12020
chr88275155182751632E068-11847
chr88275169382751743E068-11736
chr88275242482752500E068-10979
chr88275252382752586E068-10893
chr88275264882752702E068-10777
chr88275205182752101E069-11378
chr88275213682752286E069-11193
chr88275242482752500E069-10979
chr88275252382752586E069-10893
chr88275264882752702E069-10777
chr88273635982736422E070-27057
chr88273760682737656E070-25823
chr88273770482737783E070-25696
chr88274913582749745E070-13734
chr88272692182727044E071-36435
chr88272739782727713E071-35766
chr88275040382750493E071-12986
chr88275055782750622E071-12857
chr88275073382750913E071-12566
chr88275176982751905E071-11574
chr88275192082751978E071-11501
chr88275205182752101E071-11378
chr88275213682752286E071-11193
chr88275242482752500E071-10979
chr88275252382752586E071-10893
chr88275264882752702E071-10777
chr88277068982771569E0717210
chr88278429982784817E07120820
chr88272629482726439E072-37040
chr88272692182727044E072-36435
chr88272708482727145E072-36334
chr88272739782727713E072-35766
chr88272739782727713E073-35766
chr88272692182727044E074-36435
chr88275040382750493E074-12986
chr88275055782750622E074-12857
chr88275073382750913E074-12566
chr88275118682751259E074-12220
chr88275141582751459E074-12020
chr88275155182751632E074-11847
chr88275169382751743E074-11736
chr88275176982751905E074-11574
chr88275192082751978E074-11501
chr88275205182752101E074-11378
chr88275213682752286E074-11193
chr88275242482752500E074-10979
chr88275252382752586E074-10893
chr88275264882752702E074-10777
chr88278429982784817E07420820
chr88274894182748991E081-14488
chr88275118682751259E081-12220
chr88275141582751459E081-12020
chr88275155182751632E081-11847
chr88275169382751743E081-11736
chr88275176982751905E081-11574
chr88275192082751978E081-11501
chr88275205182752101E081-11378
chr88275213682752286E081-11193
chr88275242482752500E081-10979
chr88275252382752586E081-10893
chr88275264882752702E081-10777
chr88274913582749745E082-13734
chr88274982582749873E082-13606
chr88275155182751632E082-11847
chr88275169382751743E082-11736
chr88275176982751905E082-11574
chr88275192082751978E082-11501
chr88275205182752101E082-11378
chr88275213682752286E082-11193
chr88275242482752500E082-10979
chr88275252382752586E082-10893










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr88275290282753069E067-10410
chr88275314082753307E067-10172
chr88275349982753591E067-9888
chr88275360282754599E067-8880
chr88275349982753591E068-9888
chr88275360282754599E068-8880
chr88275461982755486E068-7993
chr88275290282753069E069-10410
chr88275314082753307E069-10172
chr88275349982753591E069-9888
chr88275360282754599E069-8880
chr88275290282753069E070-10410
chr88275314082753307E070-10172
chr88275349982753591E070-9888
chr88275360282754599E070-8880
chr88275290282753069E071-10410
chr88275314082753307E071-10172
chr88275349982753591E071-9888
chr88275360282754599E071-8880
chr88275461982755486E071-7993
chr88275290282753069E072-10410
chr88275314082753307E072-10172
chr88275349982753591E072-9888
chr88275360282754599E072-8880
chr88275290282753069E073-10410
chr88275314082753307E073-10172
chr88275349982753591E073-9888
chr88275360282754599E073-8880
chr88275461982755486E073-7993
chr88275314082753307E074-10172
chr88275349982753591E074-9888
chr88275360282754599E074-8880
chr88275461982755486E074-7993
chr88275360282754599E081-8880
chr88275290282753069E082-10410
chr88275314082753307E082-10172
chr88275349982753591E082-9888
chr88275360282754599E082-8880
chr88275461982755486E082-7993