rs7843718

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0049 (1485/29972,GnomAD)
G=0078 (2297/29118,TOPMED)
G=0055 (277/5008,1000G)
G=0000 (1/3854,ALSPAC)
G=0000 (1/3708,TWINSUK)
chr8:133722977 (GRCh38.p7) (8q24.22)
AD
GWASCatalog
1   publication(s)
See rs on genome
9 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.133722977A>G
GRCh37.p13 chr 8NC_000008.10:g.134735220A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.799G=0.201
1000GenomesAmericanSub694A=0.990G=0.010
1000GenomesEast AsianSub1008A=1.000G=0.000
1000GenomesEuropeSub1006A=1.000G=0.000
1000GenomesGlobalStudy-wide5008A=0.945G=0.055
1000GenomesSouth AsianSub978A=1.000G=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=1.000G=0.000
The Genome Aggregation DatabaseAfricanSub8716A=0.831G=0.169
The Genome Aggregation DatabaseAmericanSub838A=0.990G=0.010
The Genome Aggregation DatabaseEast AsianSub1622A=1.000G=0.000
The Genome Aggregation DatabaseEuropeSub18494A=0.999G=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29972A=0.950G=0.049
The Genome Aggregation DatabaseOtherSub302A=1.000G=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.921G=0.078
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=1.000G=0.000
PMID Title Author Journal
29082582Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.Almli LMAddict Biol

P-Value

SNP ID p-value Traits Study
rs78437185E-06alcohol dependence29082582

eQTL of rs7843718 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7843718 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8134758789134759145E06923569
chr8134779247134780069E06944027
chr8134686427134687568E070-47652
chr8134758367134758583E07123147
chr8134758789134759145E07123569
chr8134758063134758126E08122843
chr8134758202134758321E08122982
chr8134758367134758583E08123147
chr8134758789134759145E08123569