rs7868755

Homo sapiens
C>T
MLLT3 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0040 (1228/29994,GnomAD)
C==0041 (1197/29118,TOPMED)
C==0026 (130/5008,1000G)
C==0062 (239/3854,ALSPAC)
C==0056 (209/3708,TWINSUK)
chr9:20551929 (GRCh38.p7) (9p21.3)
ND
GWASdb2
1   publication(s)
See rs on genome
210 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.20551929C>T
GRCh37.p13 chr 9NC_000009.11:g.20551928C>T

Gene: MLLT3, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3(minus strand)

Molecule type Change Amino acid[Codon] SO Term
MLLT3 transcript variant 2NM_001286691.1:c.N/AIntron Variant
MLLT3 transcript variant 1NM_004529.3:c.N/AIntron Variant
MLLT3 transcript variant X1XM_017014726.1:c.N/AIntron Variant
MLLT3 transcript variant X2XM_017014727.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.006T=0.994
1000GenomesAmericanSub694C=0.070T=0.930
1000GenomesEast AsianSub1008C=0.011T=0.989
1000GenomesEuropeSub1006C=0.055T=0.945
1000GenomesGlobalStudy-wide5008C=0.026T=0.974
1000GenomesSouth AsianSub978C=0.010T=0.990
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.062T=0.938
The Genome Aggregation DatabaseAfricanSub8732C=0.018T=0.982
The Genome Aggregation DatabaseAmericanSub838C=0.070T=0.930
The Genome Aggregation DatabaseEast AsianSub1622C=0.020T=0.980
The Genome Aggregation DatabaseEuropeSub18500C=0.052T=0.947
The Genome Aggregation DatabaseGlobalStudy-wide29994C=0.040T=0.959
The Genome Aggregation DatabaseOtherSub302C=0.040T=0.960
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.041T=0.958
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.056T=0.944
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs78687550.000996nicotine smoking19268276

eQTL of rs7868755 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7868755 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr92055175420552458E0670
chr92055248820552581E067560
chr92055259920552691E067671
chr92055295320553001E0671025
chr92055306520553766E0671137
chr92055802420558189E0676096
chr92055843520559104E0676507
chr92056348420563774E06711556
chr92056386420563914E06711936
chr92056397820564058E06712050
chr92056843820568498E06716510
chr92050495520505302E068-46626
chr92050549920505549E068-46379
chr92050563620505839E068-46089
chr92050594420505994E068-45934
chr92052058820520746E068-31182
chr92052642720526909E068-25019
chr92055175420552458E0680
chr92055248820552581E068560
chr92055259920552691E068671
chr92055295320553001E0681025
chr92055306520553766E0681137
chr92055566220555745E0683734
chr92055843520559104E0686507
chr92055940120559467E0687473
chr92055956520559987E0687637
chr92056336220563412E06811434
chr92056348420563774E06811556
chr92056386420563914E06811936
chr92056997220570039E06818044
chr92059328320593937E06841355
chr92055175420552458E0690
chr92055248820552581E069560
chr92055259920552691E069671
chr92055295320553001E0691025
chr92055306520553766E0691137
chr92055384420553898E0691916
chr92055406620554155E0692138
chr92055566220555745E0693734
chr92055802420558189E0696096
chr92055843520559104E0696507
chr92056409620564266E06912168
chr92059328320593937E06941355
chr92050604020506090E070-45838
chr92050615220507734E070-44194
chr92052722820527278E070-24650
chr92056209320562320E07010165
chr92055049520550588E071-1340
chr92055070620551705E071-223
chr92055175420552458E0710
chr92055248820552581E071560
chr92055259920552691E071671
chr92055295320553001E0711025
chr92055306520553766E0711137
chr92055802420558189E0716096
chr92055843520559104E0716507
chr92055940120559467E0717473
chr92055956520559987E0717637
chr92056458720564720E07112659
chr92059223320592273E07140305
chr92059328320593937E07141355
chr92059453320594616E07142605
chr92060145420601608E07149526
chr92052642720526909E072-25019
chr92055175420552458E0720
chr92055248820552581E072560
chr92055259920552691E072671
chr92055295320553001E0721025
chr92055306520553766E0721137
chr92055802420558189E0726096
chr92055843520559104E0726507
chr92059328320593937E07241355
chr92051175020511969E073-39959
chr92051201520512650E073-39278
chr92051312920513204E073-38724
chr92053566220535712E073-16216
chr92053572620535786E073-16142
chr92055175420552458E0730
chr92055843520559104E0736507
chr92055940120559467E0737473
chr92056486720564917E07312939
chr92059838720598461E07346459
chr92059856920598619E07346641
chr92055175420552458E0740
chr92055259920552691E074671
chr92055295320553001E0741025
chr92055306520553766E0741137
chr92055552020555570E0743592
chr92055566220555745E0743734
chr92055843520559104E0746507
chr92056317820563238E07411250
chr92056336220563412E07411434
chr92056348420563774E07411556
chr92056386420563914E07411936
chr92056397820564058E07412050
chr92056409620564266E07412168
chr92059328320593937E07441355
chr92050495520505302E081-46626
chr92050549920505549E081-46379
chr92050563620505839E081-46089
chr92050594420505994E081-45934
chr92050604020506090E081-45838
chr92050615220507734E081-44194
chr92051175020511969E081-39959
chr92051201520512650E081-39278
chr92051267120512959E081-38969
chr92051312920513204E081-38724
chr92051325420513844E081-38084
chr92051733020517392E081-34536
chr92051748320517556E081-34372
chr92051770520517976E081-33952
chr92051876120518811E081-33117
chr92052081920520880E081-31048
chr92052148020521739E081-30189
chr92052182020522320E081-29608
chr92052239920522621E081-29307
chr92052627920526388E081-25540
chr92052642720526909E081-25019
chr92053059820530648E081-21280
chr92054899920549049E081-2879
chr92055175420552458E0810
chr92055248820552581E081560
chr92055259920552691E081671
chr92055463420554684E0812706
chr92055473420554812E0812806
chr92055490020554950E0812972
chr92055802420558189E0816096
chr92055843520559104E0816507
chr92055940120559467E0817473
chr92055956520559987E0817637
chr92056055220560602E0818624
chr92056094320560983E0819015
chr92056107220561240E0819144
chr92056147320562040E0819545
chr92056209320562320E08110165
chr92056263120562671E08110703
chr92056268820562728E08110760
chr92056277720562922E08110849
chr92056295920563137E08111031
chr92056317820563238E08111250
chr92056336220563412E08111434
chr92056348420563774E08111556
chr92056409620564266E08112168
chr92056638820566438E08114460
chr92056683420566884E08114906
chr92056693420567030E08115006
chr92056754520567603E08115617
chr92056775920567813E08115831
chr92056792120567965E08115993
chr92056802220568178E08116094
chr92056894320569056E08117015
chr92056958320569840E08117655
chr92059241320592495E08140485
chr92059802820598133E08146100
chr92059838720598461E08146459
chr92059856920598619E08146641
chr92060023120600372E08148303
chr92060046220600516E08148534
chr92050549920505549E082-46379
chr92050563620505839E082-46089
chr92050594420505994E082-45934
chr92050604020506090E082-45838
chr92050615220507734E082-44194
chr92050816720508686E082-43242
chr92051175020511969E082-39959
chr92051201520512650E082-39278
chr92051576720515872E082-36056
chr92051587720515927E082-36001
chr92051595920516016E082-35912
chr92051607020516128E082-35800
chr92051627920516379E082-35549
chr92051649220516542E082-35386
chr92052058820520746E082-31182
chr92052081920520880E082-31048
chr92052239920522621E082-29307
chr92052627920526388E082-25540
chr92052642720526909E082-25019
chr92052701220527177E082-24751
chr92052722820527278E082-24650
chr92055175420552458E0820
chr92055802420558189E0826096
chr92055843520559104E0826507
chr92055940120559467E0827473
chr92055956520559987E0827637
chr92056147320562040E0829545
chr92056209320562320E08210165
chr92056263120562671E08210703
chr92056268820562728E08210760
chr92056277720562922E08210849
chr92056295920563137E08211031
chr92056317820563238E08211250
chr92056336220563412E08211434
chr92056348420563774E08211556
chr92056386420563914E08211936
chr92056397820564058E08212050
chr92056409620564266E08212168
chr92056458720564720E08212659
chr92056683420566884E08214906
chr92056693420567030E08215006
chr92056754520567603E08215617
chr92056775920567813E08215831
chr92056792120567965E08215993
chr92056894320569056E08217015
chr92056958320569840E08217655
chr92056986620569916E08217938
chr92059027420590379E08238346
chr92059968520599826E08247757
chr92059994720600060E08248019
chr92060023120600372E08248303
chr92060145420601608E08249526