rs787176

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0340 (10190/29942,GnomAD)
C==0350 (10201/29118,TOPMED)
C==0371 (1857/5008,1000G)
C==0317 (1222/3854,ALSPAC)
C==0309 (1145/3708,TWINSUK)
chr2:143910681 (GRCh38.p7) (2q22.3)
ND
GWASdb2
1   publication(s)
See rs on genome
56 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.143910681C>T
GRCh37.p13 chr 2NC_000002.11:g.144668249C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.387T=0.613
1000GenomesAmericanSub694C=0.290T=0.710
1000GenomesEast AsianSub1008C=0.403T=0.597
1000GenomesEuropeSub1006C=0.325T=0.675
1000GenomesGlobalStudy-wide5008C=0.371T=0.629
1000GenomesSouth AsianSub978C=0.420T=0.580
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.317T=0.683
The Genome Aggregation DatabaseAfricanSub8724C=0.390T=0.610
The Genome Aggregation DatabaseAmericanSub838C=0.280T=0.720
The Genome Aggregation DatabaseEast AsianSub1612C=0.362T=0.638
The Genome Aggregation DatabaseEuropeSub18466C=0.317T=0.682
The Genome Aggregation DatabaseGlobalStudy-wide29942C=0.340T=0.659
The Genome Aggregation DatabaseOtherSub302C=0.340T=0.660
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.350T=0.649
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.309T=0.691
PMID Title Author Journal
23542338A genomewide association study of smoking relapse in four European population-based samples.Tozzi FPsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs7871766.05E-07nicotine dependence (smoking)23542338

eQTL of rs787176 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs787176 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2144695982144696253E06727733
chr2144696388144696506E06728139
chr2144696903144698125E06828654
chr2144695982144696253E06927733
chr2144649329144650013E070-18236
chr2144695982144696253E07027733
chr2144696388144696506E07028139
chr2144696537144696637E07028288
chr2144696639144696731E07028390
chr2144696783144696845E07028534
chr2144696903144698125E07028654
chr2144711200144711732E07142951
chr2144713353144713605E07145104
chr2144661137144661339E072-6910
chr2144713353144713605E07245104
chr2144698164144698234E07429915
chr2144632817144632935E081-35314
chr2144633055144633105E081-35144
chr2144633168144633470E081-34779
chr2144634716144634950E081-33299
chr2144635280144635413E081-32836
chr2144695982144696253E08127733
chr2144696388144696506E08128139
chr2144696537144696637E08128288
chr2144696639144696731E08128390
chr2144696783144696845E08128534
chr2144696903144698125E08128654
chr2144698164144698234E08129915
chr2144698319144698369E08130070
chr2144702626144702703E08134377
chr2144703445144703495E08135196
chr2144707288144707400E08139039
chr2144707426144707586E08139177
chr2144707833144707893E08139584
chr2144708037144708109E08139788
chr2144709080144709242E08140831
chr2144709395144709445E08141146
chr2144710721144710895E08142472
chr2144710967144711194E08142718
chr2144711200144711732E08142951
chr2144711805144712133E08143556
chr2144712309144712358E08144060
chr2144712388144712542E08144139
chr2144712602144712665E08144353
chr2144712828144713328E08144579
chr2144713353144713605E08145104
chr2144714393144714553E08146144
chr2144646757144647213E082-21036
chr2144696903144698125E08228654
chr2144698164144698234E08229915
chr2144698319144698369E08230070
chr2144703445144703495E08235196
chr2144710721144710895E08242472
chr2144710967144711194E08242718
chr2144712828144713328E08244579
chr2144713353144713605E08245104









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr2144692745144695958E06724496
chr2144692745144695958E06824496
chr2144692745144695958E06924496
chr2144692745144695958E07024496
chr2144692745144695958E07124496
chr2144692745144695958E07224496
chr2144692745144695958E07324496
chr2144692745144695958E07424496
chr2144692745144695958E08224496