rs789046

Homo sapiens
A>G / A>T
LOC107985165 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0100 (2998/29964,GnomAD)
G=0119 (3469/29118,TOPMED)
G=0140 (703/5008,1000G)
chr18:1020819 (GRCh38.p7) (18p11.32)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.1020819A>G
GRCh38.p7 chr 18NC_000018.10:g.1020819A>T
GRCh37.p13 chr 18NC_000018.9:g.1020820A>G
GRCh37.p13 chr 18NC_000018.9:g.1020820A>T

Gene: LOC107985165, uncharacterized LOC107985165(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107985165 transcriptXR_001753317.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.869G=0.131
1000GenomesAmericanSub694A=0.900G=0.100
1000GenomesEast AsianSub1008A=0.829G=0.171
1000GenomesEuropeSub1006A=0.908G=0.092
1000GenomesGlobalStudy-wide5008A=0.860G=0.140
1000GenomesSouth AsianSub978A=0.800G=0.200
The Genome Aggregation DatabaseAfricanSub8724A=0.865G=0.135
The Genome Aggregation DatabaseAmericanSub834A=0.910G=0.090
The Genome Aggregation DatabaseEast AsianSub1606A=0.851G=0.149
The Genome Aggregation DatabaseEuropeSub18498A=0.922G=0.077
The Genome Aggregation DatabaseGlobalStudy-wide29964A=0.899G=0.100
The Genome Aggregation DatabaseOtherSub302A=0.730G=0.270
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.880G=0.119
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs7890460.000853alcohol dependence24277619

eQTL of rs789046 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs789046 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr186562173865621803E07038640
chr186562182265621946E07038724
chr186562199065622219E07038892
chr186562229365622391E07039195
chr186560069365600785E08117595