rs789071

Homo sapiens
G>A
LOC107985165 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0102 (3063/29966,GnomAD)
A=0122 (3563/29118,TOPMED)
A=0143 (718/5008,1000G)
A=0072 (279/3854,ALSPAC)
A=0068 (252/3708,TWINSUK)
chr18:1008338 (GRCh38.p7) (18p11.32)
AD
GWASdb2
1   publication(s)
See rs on genome
10 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.1008338G>A
GRCh37.p13 chr 18NC_000018.9:g.1008339G>A

Gene: LOC107985165, uncharacterized LOC107985165(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC107985165 transcriptXR_001753317.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.829A=0.171
1000GenomesAmericanSub694G=0.910A=0.090
1000GenomesEast AsianSub1008G=0.829A=0.171
1000GenomesEuropeSub1006G=0.925A=0.075
1000GenomesGlobalStudy-wide5008G=0.857A=0.143
1000GenomesSouth AsianSub978G=0.810A=0.190
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.928A=0.072
The Genome Aggregation DatabaseAfricanSub8712G=0.831A=0.169
The Genome Aggregation DatabaseAmericanSub838G=0.920A=0.080
The Genome Aggregation DatabaseEast AsianSub1618G=0.848A=0.152
The Genome Aggregation DatabaseEuropeSub18496G=0.933A=0.066
The Genome Aggregation DatabaseGlobalStudy-wide29966G=0.897A=0.102
The Genome Aggregation DatabaseOtherSub302G=0.800A=0.200
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.877A=0.122
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.932A=0.068
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs7890710.000858alcohol dependence24277619

eQTL of rs789071 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs789071 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr18967096967243E081-41096
chr18984522984608E081-23731
chr18985114986050E081-22289
chr18984212984367E082-23972
chr18984522984608E082-23731
chr18985114986050E082-22289
chr18986113986419E082-21920
chr1810173311017471E0828992
chr1810176581018126E0829319
chr1810181381019702E0829799