SNP Detail Info-rs7904001

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0322 (9639/29870,GnomAD)
A=0326 (9497/29118,TOPMED)
A=0318 (1591/5008,1000G)
A=0283 (1089/3854,ALSPAC)
A=0280 (1040/3708,TWINSUK)

Position: chr10:65002965 (GRCh38.p7) (10q21.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 2 publication(s)

Genomic View: See rs on genome

Enhancer: 1 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 10	NC_000010.11:g.65002965G>A
GRCh37.p13 chr 10	NC_000010.10:g.66762723G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.582	A=0.418
1000Genomes	American	Sub	694	G=0.790	A=0.210
1000Genomes	East Asian	Sub	1008	G=0.753	A=0.247
1000Genomes	Europe	Sub	1006	G=0.691	A=0.309
1000Genomes	Global	Study-wide	5008	G=0.682	A=0.318
1000Genomes	South Asian	Sub	978	G=0.660	A=0.340
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.717	A=0.283
The Genome Aggregation Database	African	Sub	8702	G=0.589	A=0.411
The Genome Aggregation Database	American	Sub	824	G=0.790	A=0.210
The Genome Aggregation Database	East Asian	Sub	1614	G=0.748	A=0.252
The Genome Aggregation Database	Europe	Sub	18430	G=0.706	A=0.293
The Genome Aggregation Database	Global	Study-wide	29870	G=0.677	A=0.322
The Genome Aggregation Database	Other	Sub	300	G=0.760	A=0.240
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.673	A=0.326
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.720	A=0.280

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res
21689440	Natural selection among Eurasians at genomic regions associated with HIV-1 control.	Klimentidis YC	BMC Evol Biol

SNP ID	p-value	Traits	Study
rs7904001	0.000655	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
cg05276469	chr17:16570473		0.166211853569301	8.2879e-19

rs7904001