rs7906877

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0484 (14500/29902,GnomAD)
C==0468 (13648/29118,TOPMED)
C==0427 (2136/5008,1000G)
T=0376 (1451/3854,ALSPAC)
T=0360 (1336/3708,TWINSUK)
chr10:84044036 (GRCh38.p7) (10q23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
2 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.84044036C>T
GRCh37.p13 chr 10NC_000010.10:g.85803792C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.247T=0.753
1000GenomesAmericanSub694C=0.440T=0.560
1000GenomesEast AsianSub1008C=0.416T=0.584
1000GenomesEuropeSub1006C=0.629T=0.371
1000GenomesGlobalStudy-wide5008C=0.427T=0.573
1000GenomesSouth AsianSub978C=0.470T=0.530
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.624T=0.376
The Genome Aggregation DatabaseAfricanSub8706C=0.307T=0.693
The Genome Aggregation DatabaseAmericanSub838C=0.470T=0.530
The Genome Aggregation DatabaseEast AsianSub1618C=0.455T=0.545
The Genome Aggregation DatabaseEuropeSub18438C=0.621T=0.378
The Genome Aggregation DatabaseGlobalStudy-wide29902C=0.515T=0.484
The Genome Aggregation DatabaseOtherSub302C=0.450T=0.550
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.468T=0.531
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.640T=0.360
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs79068770.000089alcohol dependence20201924
rs79068770.0000892alcoholismpha002893
rs79068770.00014alcohol dependence(early age of onset)20201924

eQTL of rs7906877 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7906877 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr108575954585759629E070-44163
chr108575974285759810E070-43982
chr108576019985760257E070-43535

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr108580917085809315E0685378
chr108580917085809315E0715378