rs7925049

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0130 (3894/29908,GnomAD)
G=0140 (4085/29118,TOPMED)
G=0242 (1213/5008,1000G)
G=0091 (350/3854,ALSPAC)
G=0088 (328/3708,TWINSUK)
chr11:122581485 (GRCh38.p7) (11q24.1)
AD
GWASdb2
1   publication(s)
See rs on genome

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.122581485A>G
GRCh37.p13 chr 11NC_000011.9:g.122452193A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.862G=0.138
1000GenomesAmericanSub694A=0.690G=0.310
1000GenomesEast AsianSub1008A=0.533G=0.467
1000GenomesEuropeSub1006A=0.896G=0.104
1000GenomesGlobalStudy-wide5008A=0.758G=0.242
1000GenomesSouth AsianSub978A=0.750G=0.250
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.909G=0.091
The Genome Aggregation DatabaseAfricanSub8690A=0.844G=0.156
The Genome Aggregation DatabaseAmericanSub836A=0.630G=0.370
The Genome Aggregation DatabaseEast AsianSub1608A=0.544G=0.456
The Genome Aggregation DatabaseEuropeSub18474A=0.920G=0.080
The Genome Aggregation DatabaseGlobalStudy-wide29908A=0.869G=0.130
The Genome Aggregation DatabaseOtherSub300A=0.930G=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.859G=0.140
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.912G=0.088
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs79250493E-05alcoholism (heaviness of drinking)21529783

eQTL of rs7925049 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7925049 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11122499432122500097E06747239
chr11122500150122500240E06747957
chr11122469600122469660E06817407
chr11122469835122469939E06817642
chr11122469963122470042E06817770
chr11122470399122470449E06818206
chr11122499432122500097E07047239
chr11122498609122498673E07246416
chr11122499432122500097E07347239
chr11122404732122404883E081-47310
chr11122498609122498673E08146416
chr11122498962122499012E08146769
chr11122499307122499361E08147114
chr11122499432122500097E08147239
chr11122500734122500882E08148541
chr11122500899122501070E08148706
chr11122501099122501159E08148906
chr11122501181122501280E08148988
chr11122501345122501575E08149152
chr11122499432122500097E08247239







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr11122451202122452452E0670
chr11122427177122427280E068-24913
chr11122427287122427719E068-24474
chr11122427772122427869E068-24324
chr11122451202122452452E0680
chr11122427287122427719E069-24474
chr11122427772122427869E069-24324
chr11122451202122452452E0690
chr11122427287122427719E070-24474
chr11122427772122427869E070-24324
chr11122451202122452452E0700
chr11122427177122427280E071-24913
chr11122427287122427719E071-24474
chr11122427772122427869E071-24324
chr11122451202122452452E0710
chr11122427287122427719E072-24474
chr11122427772122427869E072-24324
chr11122451202122452452E0720
chr11122427177122427280E073-24913
chr11122427287122427719E073-24474
chr11122427772122427869E073-24324
chr11122451202122452452E0730
chr11122451202122452452E0810
chr11122427287122427719E082-24474
chr11122427772122427869E082-24324