SNP Detail Info-rs7930237

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

LOC101929174 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0188 (5638/29916,GnomAD)
G=0195 (5693/29118,TOPMED)
G=0164 (823/5008,1000G)
G=0235 (907/3854,ALSPAC)
G=0244 (906/3708,TWINSUK)

Position: chr11:88384794 (GRCh38.p7) (11q14.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 16 Enhancers around

Promoter: 11 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 11	NC_000011.10:g.88384794A>G
GRCh37.p13 chr 11	NC_000011.9:g.88117962A>G

Molecule type	Change	Amino acid[Codon]	SO Term
LOC101929174 transcript variant X1	XR_001748318.1:n.	N/A	Intron Variant
LOC101929174 transcript variant X2	XR_001748319.1:n.	N/A	Intron Variant
LOC101929174 transcript variant X3	XR_001748320.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.918	G=0.082
1000Genomes	American	Sub	694	A=0.770	G=0.230
1000Genomes	East Asian	Sub	1008	A=0.822	G=0.178
1000Genomes	Europe	Sub	1006	A=0.770	G=0.230
1000Genomes	Global	Study-wide	5008	A=0.836	G=0.164
1000Genomes	South Asian	Sub	978	A=0.850	G=0.150
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.765	G=0.235
The Genome Aggregation Database	African	Sub	8706	A=0.903	G=0.097
The Genome Aggregation Database	American	Sub	834	A=0.800	G=0.200
The Genome Aggregation Database	East Asian	Sub	1610	A=0.766	G=0.234
The Genome Aggregation Database	Europe	Sub	18466	A=0.775	G=0.224
The Genome Aggregation Database	Global	Study-wide	29916	A=0.811	G=0.188
The Genome Aggregation Database	Other	Sub	300	A=0.680	G=0.320
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.804	G=0.195
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.756	G=0.244

PMID	Title	Author	Journal
21956439	Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.	Zuo L	Neuropsychopharmacology

SNP ID	p-value	Traits	Study
rs7930237	9E-06	alcohol dependence	21956439

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
cg20905760	chr15:43478003	CCNDBP1	0.00901281228314821	2.3356e-9
cg03106852	chr6:112555546	LAMA4	-0.0445214164449427	3.8820e-9

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr11	88117085	88117139	E068	-823
chr11	88110901	88111115	E070	-6847
chr11	88111116	88111255	E070	-6707
chr11	88111452	88111532	E070	-6430
chr11	88111742	88111940	E070	-6022
chr11	88112000	88112050	E070	-5912
chr11	88112257	88112428	E070	-5534
chr11	88112471	88112521	E070	-5441
chr11	88147560	88148626	E070	29598
chr11	88116700	88116961	E072	-1001
chr11	88131605	88132154	E072	13643
chr11	88132495	88132555	E072	14533
chr11	88147560	88148626	E074	29598
chr11	88148686	88148883	E074	30724
chr11	88085313	88085565	E082	-32397
chr11	88085638	88085688	E082	-32274

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr11	88069641	88072234	E067	-45728
chr11	88069641	88072234	E068	-45728
chr11	88069641	88072234	E069	-45728
chr11	88069641	88072234	E070	-45728
chr11	88068990	88069390	E071	-48572
chr11	88069641	88072234	E071	-45728
chr11	88069641	88072234	E072	-45728
chr11	88069641	88072234	E073	-45728
chr11	88069641	88072234	E074	-45728
chr11	88069641	88072234	E081	-45728
chr11	88069641	88072234	E082	-45728

rs7930237