rs7933807

Homo sapiens
A>C
OR10A6 : Missense Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0417 (50166/120180,ExAC)
C=0399 (11931/29880,GnomAD)
C=0370 (10778/29118,TOPMED)
A==0377 (4900/12984,GO-ESP)
C=0413 (2069/5008,1000G)
C=0392 (1510/3854,ALSPAC)
C=0388 (1437/3708,TWINSUK)
chr11:7928244 (GRCh38.p7) (11p15.4)
AD
GWASdb2
2   publication(s)
See rs on genome
2 Enhancers around
2 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.7928244A>C
GRCh37.p13 chr 11NC_000011.9:g.7949791A>C
GRCh38.p7 chr 11 novel patch HSCHR11_1_CTG1_2NW_011332695.1:g.159238A>C
GRCh38.p7 chr 11 alt locus HSCHR11_1_CTG5NT_187583.1:g.159745A>C

Gene: OR10A6, olfactory receptor family 10 subfamily A member 6 (gene/pseudogene)(minus strand)

Molecule type Change Amino acid[Codon] SO Term
OR10A6 transcriptNM_001004461.1:c....NM_001004461.1:c.419T>GV [GTT]> G [GGT]Coding Sequence Variant
olfactory receptor 10A6NP_001004461.1:p....NP_001004461.1:p.Val140GlyV [Val]> G [Gly]Missense Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.665C=0.335
1000GenomesAmericanSub694A=0.620C=0.380
1000GenomesEast AsianSub1008A=0.506C=0.494
1000GenomesEuropeSub1006A=0.574C=0.426
1000GenomesGlobalStudy-wide5008A=0.587C=0.413
1000GenomesSouth AsianSub978A=0.560C=0.440
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.608C=0.392
The Exome Aggregation ConsortiumAmericanSub21264A=0.643C=0.356
The Exome Aggregation ConsortiumAsianSub25076A=0.517C=0.482
The Exome Aggregation ConsortiumEuropeSub72938A=0.587C=0.412
The Exome Aggregation ConsortiumGlobalStudy-wide120180A=0.582C=0.417
The Exome Aggregation ConsortiumOtherSub902A=0.570C=0.430
The Genome Aggregation DatabaseAfricanSub8692A=0.653C=0.347
The Genome Aggregation DatabaseAmericanSub838A=0.620C=0.380
The Genome Aggregation DatabaseEast AsianSub1598A=0.502C=0.498
The Genome Aggregation DatabaseEuropeSub18450A=0.585C=0.414
The Genome Aggregation DatabaseGlobalStudy-wide29880A=0.600C=0.399
The Genome Aggregation DatabaseOtherSub302A=0.500C=0.500
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.629C=0.370
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.612C=0.388
PMID Title Author Journal
26648445Distinct X-chromosome SNVs from some sporadic AD samples.Gomez-Ramos ASci Rep
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs79338075.4E-05alcohol consumption23953852

eQTL of rs7933807 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7933807 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1179858687986265E07036077
chr1179858687986265E08236077


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1179492487949467E074-324
chr1179494767949625E074-166