rs7944287

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0070 (2105/29688,GnomAD)
T==0070 (2041/29118,TOPMED)
T==0115 (575/5008,1000G)
T==0087 (334/3854,ALSPAC)
T==0089 (330/3708,TWINSUK)
chr11:48495054 (GRCh38.p7) (11p11.2)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.48495054T>C
GRCh37.p13 chr 11NC_000011.9:g.48516606T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.004C=0.996
1000GenomesAmericanSub694T=0.080C=0.920
1000GenomesEast AsianSub1008T=0.233C=0.767
1000GenomesEuropeSub1006T=0.089C=0.911
1000GenomesGlobalStudy-wide5008T=0.115C=0.885
1000GenomesSouth AsianSub978T=0.200C=0.800
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.087C=0.913
The Genome Aggregation DatabaseAfricanSub8664T=0.020C=0.980
The Genome Aggregation DatabaseAmericanSub826T=0.070C=0.930
The Genome Aggregation DatabaseEast AsianSub1580T=0.216C=0.784
The Genome Aggregation DatabaseEuropeSub18316T=0.081C=0.918
The Genome Aggregation DatabaseGlobalStudy-wide29688T=0.070C=0.929
The Genome Aggregation DatabaseOtherSub302T=0.160C=0.840
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.070C=0.929
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.089C=0.911
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs79442871.86E-05alcohol and nictotine co-dependence20158304

eQTL of rs7944287 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7944287 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.